⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11989018 | 0.83 | MGAM (0.32) | — | |
| SCHEMBL11236691 | 0.80 | — | — | |
| SCHEMBL12123157 | 0.79 | CES2 (0.31) | — | |
| SCHEMBL15131909 | 0.79 | MAPK1 (0.38) | — | |
| SCHEMBL7682659 | 0.77 | TSHR (0.41) | — | |
| SCHEMBL11131624 | 0.77 | — | — | |
| SCHEMBL431399 | 0.77 | — | — | |
| SCHEMBL6743732 | 0.76 | ALDH1A1 (0.38) | — | |
| SCHEMBL26316213 | 0.76 | DGAT1 (0.40) | — | |
| SCHEMBL4208343 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764625-B1 | Process for improving the storability of liquid hydroxy- and alkoxyalkylketones | BASF AG (DE) | 1999-04-07 | — | — | EP | claimed |
| US-5874631-A | ADDING FROM 0.0001 TO 1% BY WEIGHT OF A TERTIARY AMINE, OR GROUP 1A AND 2A HYDROXIDES AND CARBONATES OR MIXTURES THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1999-02-23 | — | — | US | claimed |
| EP-0764625-A1 | Process for improving the storability of liquid hydroxy- and alkoxyalkylketones | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-26 | — | — | EP | claimed |
| EP-4590676-A1 | HEXAHYDRO-2H-PYRIDO[2,1-A]ISOQUINOLINE VMAT2 INHIBITORS AND METHODS OF USE | Neurocrine Biosciences, Inc. (US) | 2025-07-30 | — | — | EP | disclosed |
| CN-119907800-A | Hexahydro-2H-pyrido [2,1-a ] isoquinoline VMAT2 inhibitors and methods of use thereof | 纽罗克里生物科学有限公司 | 2025-04-29 | — | — | CN | disclosed |
| WO-2024064178-A1 | HEXAHYDRO-2H-PYRIDO[2,1-A]ISOQUINOLINE VMAT2 INHIBITORS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2024-03-28 | — | — | WO | disclosed |
| US-11826328-B2 | Stable treprostinil prodrugs | UNITED THERAPEUTICS CORPORATION (US) | 2023-11-28 | — | — | US | disclosed |
| CN-117062808-A | Crystalline solid meglumine salt inhibitors of BCL and methods of making and using the same | 联合生物科技公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-111670186-B | Pyrazolopyridine-diamides, their use as pesticides and process for their preparation | PI工业有限公司 | 2023-10-17 | — | — | CN | disclosed |
| US-20230279023-A1 | N/O-Linked Degrons and Degronimers for Protein Degradation | C4 THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | US | disclosed |
| US-20230159504-A1 | 7- OR 8-HYDROXY-ISOQUINOLINE AND 7- OR 8-HYDROXY-QUINOLINE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD) | VERTEX PHARMACEUTICALS INCORPORATED | 2023-05-25 | — | — | US | disclosed |
| EP-0506068-A1 | Oxidation of terminal olefins to aldehydes | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1992-09-30 | — | — | EP | disclosed |
| US-5136105-A | Catalytic reaction in presence of alcohol | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |
| US-4515975-A | Chroman derivatives and their preparation | BASF AKTIENGESELLSCHAFT (DE) | 1985-05-07 | — | — | US | disclosed |
| EP-0052731-B1 | CHROMAN DERIVATIVES AND METHOD FOR THEIR PREPARATION | BASF Aktiengesellschaft (DE) | 1985-04-17 | — | — | EP | disclosed |
| US-4440779-A | Tricyclic derivatives of substituted pyrrole acids as analgesic and anti-inflammatory agents | MERCK & CO., INC. (US) | 1984-04-03 | — | — | US | disclosed |
| EP-0068460-A1 | Tricyclic derivatives of substituted pyrrole acids as analgesic and anti-inflammatory agents | MERCK & CO. INC. (US) | 1983-01-05 | — | — | EP | disclosed |
| EP-0052731-A1 | Chroman derivatives and method for their preparation | BASF Aktiengesellschaft (DE) | 1982-06-02 | — | — | EP | disclosed |
| US-4229262-A | EXTRACTIVE DISTILLATION | UNION CARBIDE CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |
| US-4153516-A | SOLVENT EXTRACTION WITH AN ALCOHOL SOLVENT | UNION CARBIDE CORPORATION (US) | 1979-05-08 | — | — | US | disclosed |