SCHEMBL15344609

SCHEMBL15344609

CCCCOC(=O)c1cccc(OCCC)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.66
ADRB2 P07550 1/20 0.59
ADRB1 P08588 1/20 0.59
ADRB3 P13945 1/20 0.59
SMPD1 P17405 3/20 0.57
PLA2G4B P0C869 1/20 0.56
THRB P10828 1/20 0.56
NR1H4 Q96RI1 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
TDP1 Q9NUW8 1/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2C19 P33261 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
NPC1 O15118 1/20 0.53
CYP2C9 P11712 1/20 0.53
HPGD P15428 1/20 0.53
RAB9A P51151 1/20 0.53
LMNA P02545 2/20 0.53
ESR1 P03372 3/20 0.53
CYP2D6 P10635 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17961071 0.97 KMT2A (0.60) KMT2AADRB2ADRB1ADRB3SMPD1
SCHEMBL11347541 0.93 SMPD1 (0.67) KMT2ASMPD1PLA2G4BTHRBNR1H4
SCHEMBL17961066 0.93 SMPD1 (0.66) KMT2AADRB2ADRB1ADRB3SMPD1
SCHEMBL7905955 0.92 KMT2A (0.71) KMT2AADRB2ADRB1ADRB3SMPD1
SCHEMBL15344575 0.91 CYP1A2 (0.56) KMT2ASMPD1PLA2G4BL3MBTL1TDP1
SCHEMBL17961074 0.91 SMPD1 (0.68) KMT2ASMPD1PLA2G4BTHRBNR1H4
SCHEMBL17961053 0.91 SMPD1 (0.68) KMT2ASMPD1PLA2G4BTHRBNR1H4
SCHEMBL17961060 0.91 SMPD1 (0.68) KMT2ASMPD1PLA2G4BTHRBNR1H4
SCHEMBL27914875 0.90 KMT2A (0.57) KMT2AADRB2ADRB1ADRB3SMPD1
SCHEMBL27803200 0.90 KMT2A (0.57) KMT2AADRB2ADRB1ADRB3SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102834420-B Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP. (US) 2014-10-22 CN claimed
US-8569195-B2 Internal and external donor compounds for olefin polymerization catalysts II BASF CORPORATION (US) 2013-10-29 US claimed
CN-102834420-A Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP 2012-12-19 CN claimed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP disclosed
CN-102834420-B Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP. (US) 2014-10-22 CN disclosed
CN-102834420-A Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP 2012-12-19 CN disclosed