Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.63 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15344609 | 0.92 | KMT2A (0.66) | KMT2AADRB2ADRB1ADRB3LMNA | |
| SCHEMBL11749290 | 0.92 | KMT2A (0.60) | KMT2AADRB2ADRB1ADRB3LMNA | |
| SCHEMBL931897 | 0.92 | KMT2A (0.69) | KMT2AADRB2ADRB1ADRB3LMNA | |
| SCHEMBL23627035 | 0.91 | SMPD1 (0.67) | KMT2AADRB2ADRB1ADRB3LMNA | |
| SCHEMBL17961071 | 0.89 | KMT2A (0.60) | KMT2AADRB2ADRB1ADRB3LMNA | |
| SCHEMBL17961066 | 0.88 | SMPD1 (0.66) | KMT2AADRB2ADRB1ADRB3LMNA | |
| SCHEMBL9174494 | 0.87 | KMT2A (0.59) | KMT2AADRB2ADRB1ADRB3LMNA | |
| SCHEMBL11505600 | 0.87 | SMN1; SMN2 (0.70) | KMT2ALMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL22497897 | 0.87 | LMNA (0.62) | KMT2AADRB2ADRB1ADRB3LMNA | |
| SCHEMBL2340354 | 0.87 | KMT2A (0.71) | KMT2AADRB2ADRB1ADRB3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102834420-B | Internal and external donor compounds for olefin polymerization catalysts ii | BASF CORP. (US) | 2014-10-22 | — | — | CN | claimed |
| US-8569195-B2 | Internal and external donor compounds for olefin polymerization catalysts II | BASF CORPORATION (US) | 2013-10-29 | — | — | US | claimed |
| CN-102834420-A | Internal and external donor compounds for olefin polymerization catalysts ii | BASF CORP | 2012-12-19 | — | — | CN | claimed |
| US-9499528-B2 | Class of near infrared molecular probes for biological applications | THE UNIVERSITY OF AKRON (US) | 2016-11-22 | — | — | US | disclosed |
| US-9499528-B2 | Class of near infrared molecular probes for biological applications | THE UNIVERSITY OF AKRON (US) | 2016-11-22 | — | — | US | disclosed |
| EP-2782938-B1 | HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION | BASF CORP (US) | 2016-08-31 | — | — | EP | disclosed |
| US-20160221921-A1 | SKIN WHITENING AGENT CONTAINING NOVEL CYCLIC COMPOUND | RNS CO.,LTD. (KR) | 2016-08-04 | — | — | US | disclosed |
| CN-104981452-A | Skin whitening agent containing novel cyclic compound | RNS CO LTD | 2015-10-14 | — | — | CN | disclosed |
| CN-102834420-B | Internal and external donor compounds for olefin polymerization catalysts ii | BASF CORP. (US) | 2014-10-22 | — | — | CN | disclosed |
| US-20140303376-A1 | CLASS OF NEAR INFRARED MOLECULAR PROBES FOR BIOLOGICAL APPLICATIONS | THE UNIVERSITY OF AKRON | 2014-10-09 | — | — | US | disclosed |
| US-20140303376-A1 | CLASS OF NEAR INFRARED MOLECULAR PROBES FOR BIOLOGICAL APPLICATIONS | THE UNIVERSITY OF AKRON | 2014-10-09 | — | — | US | disclosed |
| CN-102834420-A | Internal and external donor compounds for olefin polymerization catalysts ii | BASF CORP | 2012-12-19 | — | — | CN | disclosed |
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303376-A1 | CLASS OF NEAR INFRARED MOLECULAR PROBES FOR BIOLOGICAL APPLICATIONS | ZKSCAN2, ZRANB2, ZNF787 | KMT2A 4173/4885ADRB2 2710/4885ADRB1 1583/4885 |
| US-20160221921-A1 | SKIN WHITENING AGENT CONTAINING NOVEL CYCLIC COMPOUND | H1-10, HCN1, HCN4 | KMT2A 712/4885ADRB2 1386/4885ADRB1 862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.