Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.60 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15344564 | 0.91 | CYP4F2 (0.61) | LMNACYP4F2CYP4A11ALDH1A1TSHR | |
| SCHEMBL3033016 | 0.90 | LMNA (0.66) | LMNACYP4F2CYP4A11ALDH1A1TSHR | |
| SCHEMBL7476830 | 0.89 | LMNA (0.57) | LMNACYP4F2CYP4A11ALDH1A1TSHR | |
| SCHEMBL12035616 | 0.89 | CYP4F2 (0.75) | CYP4F2CYP4A11ALDH1A1TSHRKDM4E | |
| SCHEMBL19350853 | 0.88 | CYP4F2 (0.62) | LMNACYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL3012847 | 0.87 | LMNA (0.54) | LMNACYP4F2CYP4A11ALDH1A1TSHR | |
| SCHEMBL20012766 | 0.87 | CYP4F2 (0.53) | LMNACYP4F2CYP4A11ALDH1A1SMN1; SMN2 | |
| SCHEMBL29579787 | 0.87 | LMNA (0.54) | LMNACYP4F2CYP4A11ALDH1A1TSHR | |
| SCHEMBL13291593 | 0.86 | CYP4F2 (0.62) | LMNACYP4F2CYP4A11ALDH1A1TSHR | |
| SCHEMBL111664 | 0.86 | LMNA (0.75) | LMNAALDH1A1TSHRESR1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102834420-B | Internal and external donor compounds for olefin polymerization catalysts ii | BASF CORP. (US) | 2014-10-22 | — | — | CN | claimed |
| US-8569195-B2 | Internal and external donor compounds for olefin polymerization catalysts II | BASF CORPORATION (US) | 2013-10-29 | — | — | US | claimed |
| CN-102834420-A | Internal and external donor compounds for olefin polymerization catalysts ii | BASF CORP | 2012-12-19 | — | — | CN | claimed |
| EP-2782938-B1 | HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION | BASF CORP (US) | 2016-08-31 | — | — | EP | disclosed |
| CN-102834420-B | Internal and external donor compounds for olefin polymerization catalysts ii | BASF CORP. (US) | 2014-10-22 | — | — | CN | disclosed |
| CN-102834420-A | Internal and external donor compounds for olefin polymerization catalysts ii | BASF CORP | 2012-12-19 | — | — | CN | disclosed |