Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9883940 | 0.93 | TSHR (0.46) | TSHRAPPCA2EPHX2BLM | |
| SCHEMBL4662528 | 0.91 | TSHR (0.45) | TSHRAPPCA2EPHX2BLM | |
| Tetrabuthylammonium SCHEMBL15345872 | 0.86 | SLC22A1 (0.40) | TSHRCA2EPHX2BLMCES2 | |
| SCHEMBL1261334 | 0.83 | — | — | |
| SCHEMBL27175669 | 0.83 | APP (0.46) | APPCA2EPHX2BLMPTGS1 | |
| SCHEMBL27175667 | 0.83 | APP (0.46) | APPCA2EPHX2BLMPTGS1 | |
| SCHEMBL11756346 | 0.83 | APP (0.46) | APPCA2EPHX2BLMCES2 | |
| SCHEMBL28042194 | 0.83 | APP (0.46) | APPCA2EPHX2BLMPTGS1 | |
| SCHEMBL8459073 | 0.81 | TSHR (0.38) | TSHRAPPBLMPTGS1PDE4A | |
| SCHEMBL15297848 | 0.79 | TSHR (0.37) | TSHRAPPBLMPTGS1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279192-B1 | IONIC LIQUIDS | MERCK PATENT GMBH (DE) | 2013-10-30 | — | — | EP | claimed |