Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.82 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.82 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.82 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.82 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.56 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | KDM5C | P41229 | 3/20 | 0.50 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.50 |
| ▸ | KDM6B | O15054 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL8834515 | 0.95 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL29055436 | 0.95 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL5712999 | 0.95 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL2583036 | 0.95 | — | — | |
| Succinic Acid SCHEMBL9655214 | 0.95 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL2715362 | 0.95 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL8785695 | 0.95 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL22471654 | 0.95 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL22217475 | 0.95 | LMNA (0.90) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL610172 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108190948-B | Method for synthesizing titanium dioxide with high specific surface area | 江苏奥净嘉环保科技有限公司 | 2019-12-20 | — | — | CN | claimed |
| CN-108190948-A | Method for synthesizing titanium dioxide with high specific surface area | 江苏奥净嘉环保科技有限公司 | 2018-06-22 | — | — | CN | claimed |
| CN-113631040-B | Compositions and methods for controlling plant pests and improving plant health | 农业生物群落股份有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-113973845-B | Compositions and methods for controlling plant disease | 农业生物群落股份有限公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-113163771-B | Compositions and methods for controlling plant pests and improving plant health | 农业生物群落股份有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-114173562-A | Compositions and methods for improving plant health and controlling plant disease | 农业生物群落股份有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-113973845-A | Compositions and methods for controlling plant disease | 农业生物群落股份有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-113631040-A | Compositions and methods for controlling plant pests and improving plant health | 农业生物群落股份有限公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-108135178-B | Compositions and methods for controlling plant disease | 农业生物群落股份有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-113163771-A | Compositions and methods for controlling plant pests and improving plant health | 农业生物群落股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-108190948-B | Method for synthesizing titanium dioxide with high specific surface area | 江苏奥净嘉环保科技有限公司 | 2019-12-20 | — | — | CN | disclosed |
| US-10058092-B2 | Apparatus and method for controlled release of botanical fumigant pesticides | SUMATICS, LLC (US) | 2018-08-28 | — | — | US | disclosed |
| CN-108190948-A | Method for synthesizing titanium dioxide with high specific surface area | 江苏奥净嘉环保科技有限公司 | 2018-06-22 | — | — | CN | disclosed |
| CN-107250318-A | Super concentrate additive solution composition | 布拉斯通产品公司 | 2017-10-13 | — | — | CN | disclosed |
| US-20130295153-A1 | Apparatus and Method for Controlled Release of Botanical Fumigant Pesticides | SUMATICS, LLC | 2013-11-07 | — | — | US | disclosed |