Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1048624 | 0.94 | — | — | |
| Cysteamine SCHEMBL2710869 | 0.74 | CYP3A4 (0.61) | — | |
| SCHEMBL1050334 | 0.70 | — | — | |
| Ethylenediamine SCHEMBL506140 | 0.68 | — | — | |
| SCHEMBL627694 | 0.68 | — | — | |
| Ethylenediamine SCHEMBL3412753 | 0.68 | NFKB1 (0.44) | — | |
| Ethylenediamine SCHEMBL506541 | 0.68 | — | — | |
| SCHEMBL2121281 | 0.67 | — | — | |
| SCHEMBL28728173 | 0.67 | — | — | |
| SCHEMBL22912475 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006452-B2 | Method for imaging zinc activation within a mitochondrion using a two-photon fluorescent probe, and method for manufacturing the two-photon fluorescent probe | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2015-04-14 | — | — | US | disclosed |
| US-20130295599-A1 | Method for Imaging Zinc Activation within a Mitochondrion Using a Two-Photon Fluorescent Probe, and Method for Manufacturing the Two-Photon Fluorescent Probe | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2013-11-07 | — | — | US | disclosed |