Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15364425 | 0.74 | ALDH1A1 (0.47) | FBP1ALDH1A1TSHRAKR1C3HTT | |
| SCHEMBL15364420 | 0.74 | ALDH1A1 (0.47) | FBP1ALDH1A1TSHRAKR1C3HTT | |
| SCHEMBL15364419 | 0.70 | ESR1 (0.35) | MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL16041245 | 0.70 | DAO (0.31) | MAPTKMT2A | |
| SCHEMBL4612517 | 0.69 | CYP2D6 (0.46) | FBP1ALDH1A1TSHRAKR1C3MAPT | |
| SCHEMBL6260556 | 0.69 | CYP2D6 (0.46) | FBP1ALDH1A1TSHRAKR1C3MAPT | |
| SCHEMBL15364145 | 0.69 | ALDH1A1 (0.50) | FBP1ALDH1A1TSHRAKR1C3HTT | |
| SCHEMBL15364147 | 0.69 | ALDH1A1 (0.50) | FBP1ALDH1A1TSHRAKR1C3HTT | |
| SCHEMBL15364965 | 0.66 | ALDH1A1 (0.47) | FBP1ALDH1A1TSHRAKR1C3HTT | |
| SCHEMBL15364962 | 0.66 | ALDH1A1 (0.47) | FBP1ALDH1A1TSHRAKR1C3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868805-B2 | Polydienes and diene copolymers having organophosphine functionality | BRIDGESTONE CORPORATION (JP) | 2018-01-16 | — | — | US | disclosed |
| EP-2844678-B1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | BRIDGESTONE CORP (JP) | 2017-02-22 | — | — | EP | disclosed |
| US-9499651-B2 | Copolymers of conjugated dienes and vinyl organophosphines prepared by anionic polymerization | BRIDGESTONE CORPORATION (JP) | 2016-11-22 | — | — | US | disclosed |
| US-9127109-B2 | Preparation of functional polymers phosphorus-containing organometal initiators | BRIDGESTONE CORPORATION (JP) | 2015-09-08 | — | — | US | disclosed |
| US-20150126675-A1 | Polydienes And Diene Copolymers Having Organophosphine Functionality | BRIDGESTONE CORPORATION (JO) | 2015-05-07 | — | — | US | disclosed |
| US-20140275428-A1 | Copolymers Of Conjugated Dienes And Vinyl Organophosphines Prepared By Anionic Polymerization | BRIDGESTONE CORPORATION (JP) | 2014-09-18 | — | — | US | disclosed |
| US-20130296480-A1 | PREPARATION OF FUNCTIONAL POLYMERS PHOSPHORUS-CONTAINING ORGANOMETAL INITIATORS | BRIDGESTONE CORPORATION (JP) | 2013-11-07 | — | — | US | disclosed |