Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL893856 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TTRCHRM2CHRM5CHRM3 | |
| Tetrahydrofuran SCHEMBL209705 | 0.97 | — | — | |
| Propylene Oxide SCHEMBL5703388 | 0.94 | ALDH1A1 (0.50) | ALDH1A1CHRM2CHRM5CHRM3CHRM4 | |
| Propylene Oxide SCHEMBL27902062 | 0.94 | ALDH1A1 (0.50) | ALDH1A1CHRM2CHRM5CHRM3CHRM4 | |
| Propylene Oxide SCHEMBL5703236 | 0.94 | ALDH1A1 (0.50) | ALDH1A1CHRM2CHRM5CHRM3CHRM4 | |
| Tetrahydrofuran SCHEMBL7167854 | 0.87 | ALDH1A1 (0.38) | ALDH1A1 | |
| Propylene Oxide SCHEMBL10532443 | 0.87 | TSHR (0.43) | TTRCHRM2CHRM5CHRM3CHRM4 | |
| Propylene Oxide SCHEMBL2992333 | 0.87 | TTR (0.39) | TTRCHRM2CHRM5CHRM3CHRM4 | |
| Propylene Oxide SCHEMBL5157871 | 0.87 | TTR (0.39) | TTRCHRM2CHRM5CHRM3CHRM4 | |
| Propylene Oxide SCHEMBL19252817 | 0.87 | TTR (0.39) | TTRCHRM2CHRM5CHRM3CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2662400-B1 | Block type-modified organopolysiloxane, method for using the organopolysiloxane, cosmetic, and method for producing the organopolysiloxane | SHINETSU CHEMICAL CO (JP) | 2017-09-13 | — | — | EP | disclosed |
| US-9078836-B2 | Block type-modified organopolysiloxane, method for using the organopolysiloxane, cosmetic, and method for producing the organopolysiloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-07-14 | — | — | US | disclosed |
| US-20130302263-A1 | BLOCK TYPE-MODIFIED ORGANOPOLYSILOXANE, METHOD FOR USING THE ORGANOPOLYSILOXANE, COSMETIC, AND METHOD FOR PRODUCING THE ORGANOPOLYSILOXANE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-11-14 | — | — | US | disclosed |
| EP-2662400-A2 | Block type-modified organopolysiloxane, method for using the organopolysiloxane, cosmetic, and method for producing the organopolysiloxane | Shin-Etsu Chemical Co., Ltd. (JP) | 2013-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130302263-A1 | BLOCK TYPE-MODIFIED ORGANOPOLYSILOXANE, METHOD FOR USING THE ORGANOPOLYSILOXANE, COSMETIC, AND METHOD FOR PRODUCING THE ORGANOPOLYSILOXANE | H1-0, H1-4, H1-2 | ALDH1A1 1806/4885TTR 1058/4885CHRM2 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.