Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 6/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2303102 | 0.73 | PARP1 (0.49) | CYP3A4PARP1ADORA3KDM4ENUDT1 | |
| SCHEMBL3817890 | 0.73 | PARP1 (0.49) | CYP3A4PARP1ADORA3KDM4ENUDT1 | |
| SCHEMBL1983703 | 0.70 | PARP1 (0.49) | PARP1ADORA3KDM4ENUDT1KCNMA1 | |
| SCHEMBL28986906 | 0.70 | PARP1 (0.49) | CYP3A4PARP1ADORA3KDM4ENUDT1 | |
| SCHEMBL28893532 | 0.70 | PARP1 (0.49) | CYP3A4PARP1ADORA3KDM4ENUDT1 | |
| SCHEMBL30267530 | 0.69 | GRM4 (0.48) | CYP3A4PARP1GRM4CYP1A2POLB | |
| SCHEMBL4023424 | 0.68 | RIPK1 (0.46) | CYP3A4KDM4EMAPT | |
| SCHEMBL18237558 | 0.67 | PARP1 (0.45) | PARP1ADORA3KDM4ENUDT1KCNMA1 | |
| SCHEMBL1681360 | 0.67 | PARP1 (0.45) | PARP1ADORA3KDM4ENUDT1KCNMA1 | |
| SCHEMBL514543 | 0.66 | HTT (0.50) | KDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8771462-B2 | Coated thermoplastic articles with removable coating | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2014-07-08 | — | — | US | disclosed |
| US-20130299097-A1 | COATED THERMOPLASTIC ARTICLES WITH REMOVABLE COATING | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2013-11-14 | — | — | US | disclosed |