Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12585035 | 0.84 | MEN1 (0.76) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL28983376 | 0.84 | CYP1A2 (0.74) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL4842646 | 0.81 | CYP1A2 (0.71) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL22315220 | 0.81 | CYP1A2 (0.71) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL4008435 | 0.81 | CYP1A2 (0.70) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL3778262 | 0.80 | CYP1A2 (0.69) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL27821451 | 0.77 | CYP1A2 (0.64) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL6864414 | 0.71 | — | — | |
| SCHEMBL13347808 | 0.70 | L3MBTL1 (0.69) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1715276 | 0.69 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969332-B2 | Aryloxy dihalopropenyl ether compounds and uses thereof | SINOCHEM CORPORATION (CN) | 2015-03-03 | — | — | US | disclosed |
| US-8969332-B2 | Aryloxy dihalopropenyl ether compounds and uses thereof | SINOCHEM CORPORATION (CN) | 2015-03-03 | — | — | US | disclosed |
| US-8969332-B2 | Aryloxy dihalopropenyl ether compounds and uses thereof | SINOCHEM CORPORATION (CN) | 2015-03-03 | — | — | US | disclosed |
| EP-2692723-A1 | ARYLOXY DIHALOPROPENYL ETHER COMPOUND AND USE THEREOF | Sinochem Corporation (CN) | 2014-02-05 | — | — | EP | disclosed |
| EP-2692723-A1 | ARYLOXY DIHALOPROPENYL ETHER COMPOUND AND USE THEREOF | Sinochem Corporation (CN) | 2014-02-05 | — | — | EP | disclosed |
| US-20130303541-A1 | ARYLOXY DIHALOPROPENYL ETHER COMPOUNDS AND USES THEREOF | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2013-11-14 | — | — | US | disclosed |
| US-20130303541-A1 | ARYLOXY DIHALOPROPENYL ETHER COMPOUNDS AND USES THEREOF | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2013-11-14 | — | — | US | disclosed |
| US-20130303541-A1 | ARYLOXY DIHALOPROPENYL ETHER COMPOUNDS AND USES THEREOF | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2013-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303541-A1 | ARYLOXY DIHALOPROPENYL ETHER COMPOUNDS AND USES THEREOF | DDT, CYP4B1, AADAC | CYP1A2 9/4885CYP2C9 25/4885CYP2C19 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.