Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL1537978 | 0.98 | ATM (0.42) | ATMBRD4ALDH1A1TSHRPOLB | |
| SCHEMBL19088338 | 0.92 | ATM (0.41) | ATMBRD4ALDH1A1TSHRPOLB | |
| SCHEMBL26830530 | 0.85 | ATM (0.42) | ATMBRD4ALDH1A1TSHRPOLB | |
| SCHEMBL25299400 | 0.84 | ATM (0.39) | ATMBRD4ALDH1A1TSHRPOLB | |
| SCHEMBL11996073 | 0.84 | ATM (0.36) | ATMBRD4ALDH1A1TSHRPOLB | |
| SCHEMBL28179054 | 0.83 | ATM (0.41) | ATMBRD4ALDH1A1TSHRPOLB | |
| SCHEMBL2289941 | 0.81 | — | — | |
| SCHEMBL663919 | 0.80 | ATM (0.50) | ATMBRD4ALDH1A1TSHRPOLB | |
| SCHEMBL6736700 | 0.79 | POLB (0.46) | ATMBRD4ALDH1A1POLBLMNA | |
| SCHEMBL15543674 | 0.79 | TSHR (0.44) | ATMBRD4ALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784441-B1 | A HIGH LOADING FUNCTIONAL RESIN | NOVO NORDISK AS (DK) | 2011-03-09 | — | — | EP | disclosed |
| US-20080319097-A1 | Polyether Polymer Matrix | VERSAMATRIX A/S (DK) | 2008-12-25 | — | — | US | disclosed |
| EP-1784441-A1 | A HIGH LOADING FUNCTIONAL RESIN | VersaMatrix A/S (DK) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006021217-A1 | A HIGH LOADING FUNCTIONAL RESIN | VERSAMATRIX A/S (DK) | 2006-03-02 | — | — | WO | disclosed |