Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11996078 | 0.92 | ATM (0.34) | ATMTSHRPOLBBRD4RECQL | |
| SCHEMBL3472392 | 0.86 | ATM (0.42) | ATMTSHRPOLBRECQLALDH1A1 | |
| SCHEMBL1538030 | 0.84 | ATM (0.43) | ATMTSHRPOLBBRD4RECQL | |
| Water SCHEMBL1537978 | 0.82 | ATM (0.42) | ATMTSHRPOLBBRD4RECQL | |
| SCHEMBL11964818 | 0.81 | CYP4F2 (0.33) | — | |
| SCHEMBL14086684 | 0.78 | USP2 (0.33) | — | |
| SCHEMBL25299400 | 0.77 | ATM (0.39) | ATMTSHRPOLBBRD4RECQL | |
| SCHEMBL19088338 | 0.77 | ATM (0.41) | ATMTSHRPOLBBRD4RECQL | |
| SCHEMBL18372454 | 0.76 | — | — | |
| SCHEMBL31463769 | 0.76 | TSHR (0.41) | ATMTSHRPOLBRECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9999576-B2 | Dental composition | DENTSPLY DETREY GMBH (DE) | 2018-06-19 | — | — | US | disclosed |
| US-20170252271-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2017-09-07 | — | — | US | disclosed |
| US-9682019-B2 | Dental composition | Dentsply DeTry GmbH (DE) | 2017-06-20 | — | — | US | disclosed |
| US-20120214900-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2012-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170252271-A1 | DENTAL COMPOSITION | COG1, PICALM, TUBGCP3 | ATM 3121/4885TSHR 4690/4885POLB 264/4885 |
| US-20120214900-A1 | DENTAL COMPOSITION | PICALM, COIL, COG1 | ATM 3136/4885TSHR 2527/4885POLB 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.