Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL743878 | 1.00 | FFAR3 (0.58) | — | |
| Acetic Acid SCHEMBL8514161 | 0.85 | — | — | |
| Acetic Acid SCHEMBL27636048 | 0.85 | FFAR3 (0.50) | — | |
| Acetic Acid SCHEMBL28252105 | 0.85 | — | — | |
| Acetic Acid SCHEMBL16908432 | 0.85 | FOLH1 (0.58) | — | |
| Acetic Acid SCHEMBL29524633 | 0.85 | FOLH1 (0.58) | — | |
| Acetic Acid SCHEMBL8327416 | 0.83 | — | — | |
| Acetic Acid SCHEMBL4032886 | 0.82 | — | — | |
| Acetic Acid SCHEMBL28515234 | 0.82 | — | — | |
| Acetic Acid SCHEMBL9659460 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848647-B1 | NATURAL RUBBER, RUBBER COMPOSITION COMPRISING NATURAL RUBBER AND METHOD FOR PRODUCING SAME, AND TIRE | BRIDGESTONE CORP (JP) | 2017-08-30 | — | — | EP | disclosed |
| EP-2848647-A1 | NATURAL RUBBER, RUBBER COMPOSITION COMPRISING NATURAL RUBBER AND METHOD FOR PRODUCING SAME, AND TIRE | Bridgestone Corporation (JP) | 2015-03-18 | — | — | EP | disclosed |
| US-20130303681-A1 | NATURAL RUBBER, RUBBER COMPOSITION CONTAINING NATURAL RUBBER, AND THE PRODUCTION PROCESS OF THE SAME, AND TIRE | BRIDGESTONE CORPORATION (JP) | 2013-11-14 | — | — | US | disclosed |