Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | THPO | P40225 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL15380491 | 1.00 | — | — | |
| Acetic Acid SCHEMBL8514161 | 0.85 | — | — | |
| Acetic Acid SCHEMBL27636048 | 0.85 | FFAR3 (0.50) | FFAR3LCKFYNFOLH1ACE | |
| Acetic Acid SCHEMBL28252105 | 0.85 | — | — | |
| Acetic Acid SCHEMBL16908432 | 0.85 | FOLH1 (0.58) | FFAR3LCKFYNFOLH1LMNA | |
| Acetic Acid SCHEMBL29524633 | 0.85 | FOLH1 (0.58) | FFAR3LCKFYNFOLH1LMNA | |
| Acetic Acid SCHEMBL8327416 | 0.83 | — | — | |
| Acetic Acid SCHEMBL4032886 | 0.82 | — | — | |
| Acetic Acid SCHEMBL28515234 | 0.82 | — | — | |
| Acetic Acid SCHEMBL9659460 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871846-A1 | INKJET INKS COMPRISING MODIFIED PIGMENTS HAVING ATTACHED POLYMERIC GROUPS | CABOT CORPORATION (US) | 2008-01-02 | — | — | EP | claimed |
| US-20060211791-A1 | Inkjet inks comprising modified pigments having attached polymeric groups | CABOT CORPORATION | 2006-09-21 | — | — | US | claimed |
| WO-2006086660-A1 | INKJET INKS COMPRISING MODIFIED PIGMENTS HAVING ATTACHED POLYMERIC GROUPS | CABOT CORPORATION (US) | 2006-08-17 | — | — | WO | claimed |
| US-20170306157-A1 | Modified Colorants and Inkjet Ink Compositions Comprising Modified Colorants | CABOT CORP (US) | 2017-10-26 | — | — | US | disclosed |
| US-9732227-B2 | Modified colorants and inkjet ink compositions comprising modified colorants | CABOT CORPORATION (US) | 2017-08-15 | — | — | US | disclosed |
| EP-3040382-A1 | MODIFIED COLORANTS AND INKJET INK COMPOSITIONS COMPRISING MODIFIED COLORANTS | Cabot Corporation (US) | 2016-07-06 | — | — | EP | disclosed |
| US-20160075880-A1 | Modified Colorants and Inkjet Ink Compositions Comprising Modified Colorants | CABOT CORPORATION | 2016-03-17 | — | — | US | disclosed |
| EP-2431427-B1 | Modified colorants and inkjet ink compositions comprising modified colorants | CABOT CORP (US) | 2014-12-31 | — | — | EP | disclosed |
| US-8858695-B2 | Modified colorants and inkjet ink compositions comprising modified colorants | CABOT CORPORATION (US) | 2014-10-14 | — | — | US | disclosed |
| CN-101379143-B | Modified colorants and inkjet ink compositions comprising modified colorants | CABOT CORP | 2014-02-12 | — | — | CN | disclosed |
| EP-2431426-A1 | Modified colorants and inkjet ink compositions comprising modified colorants | Cabot Corporation (US) | 2012-03-21 | — | — | EP | disclosed |
| EP-2431427-A1 | Modified colorants and inkjet ink compositions comprising modified colorants | Cabot Corporation (US) | 2012-03-21 | — | — | EP | disclosed |
| EP-2431425-A1 | Modified colorants and inkjet ink compositions comprising modified colorants | Cabot Corporation (US) | 2012-03-21 | — | — | EP | disclosed |
| CN-101379143-A | Modified colorants and inkjet ink compositions comprising modified colorants | CABOT CORP (US) | 2009-03-04 | — | — | CN | disclosed |
| EP-1951821-A2 | MODIFIED COLORANTS AND INKJET INK COMPOSITIONS COMPRISING MODIFIED COLORANTS | Cabot Corporation (US) | 2008-08-06 | — | — | EP | disclosed |
| EP-1871846-A1 | INKJET INKS COMPRISING MODIFIED PIGMENTS HAVING ATTACHED POLYMERIC GROUPS | CABOT CORPORATION (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2007053564-A2 | MODIFIED COLORANTS AND INKJET INK COMPOSITIONS COMPRISING MODIFIED COLORANTS | CABOT CORPORATION (US) | 2007-05-10 | — | — | WO | disclosed |
| US-20070100024-A1 | Modified colorants and inkjet ink compositions comprising modified colorants | CABOT CORPORATION | 2007-05-03 | — | — | US | disclosed |
| US-20060211791-A1 | Inkjet inks comprising modified pigments having attached polymeric groups | CABOT CORPORATION | 2006-09-21 | — | — | US | disclosed |
| WO-2006086660-A1 | INKJET INKS COMPRISING MODIFIED PIGMENTS HAVING ATTACHED POLYMERIC GROUPS | CABOT CORPORATION (US) | 2006-08-17 | — | — | WO | disclosed |