⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971586 | 0.91 | TSHR (0.30) | — | |
| SCHEMBL839012 | 0.74 | TSHR (0.38) | — | |
| SCHEMBL838326 | 0.74 | — | — | |
| SCHEMBL619109 | 0.74 | TSHR (0.38) | — | |
| SCHEMBL3481746 | 0.73 | — | — | |
| SCHEMBL12677819 | 0.73 | — | — | |
| SCHEMBL12677627 | 0.73 | — | — | |
| SCHEMBL28593332 | 0.71 | TSHR (0.35) | — | |
| SCHEMBL28595185 | 0.71 | TSHR (0.35) | — | |
| SCHEMBL14087111 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957120-A | Alkenyl homopiperidine compound and preparation method thereof | 苏州大学 | 2022-08-30 | — | — | CN | claimed |
| US-5869472-A | Synthesis of 1α-hydroxy vitamin D | BONE CARE INTERNATIONAL, INC. (US) | 1999-02-09 | — | — | US | claimed |
| EP-0865427-A1 | SYNTHESIS OF 1ALPHA-HYDROXY VITAMIN D | BONE CARE INTERNATIONAL, INC. (US) | 1998-09-23 | — | — | EP | claimed |
| WO-1996002501-A1 | SYNTHESIS OF 1α-HYDROXY VITAMIN D | LUNAR CORPORATION (US) | 1996-02-01 | — | — | WO | claimed |
| EP-0033538-A2 | 6(R)-(2-(8'-acyloxy-2'-methyl-6'-methyl (or hydrogen)-polyhydronaphthyl-1')-ethyl)-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-ones, the hydroxy acid form of said pyranones, the pharmaceutically acceptable salts of said hydroxy acids, and the lower alkyl, and phenyl, dimethylamino or acetylamino substituted lower alkyl esters of said hydroxy acid, processes for preparing the same, and a pharmaceutical antihypercholesterolemic composition containing the same | MERCK & CO. INC. (US) | 1981-08-12 | — | — | EP | claimed |
| CN-116023537-B | Catalyst composition for olefin polymerization and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-116023537-A | Catalyst composition for olefin polymerization and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-114957120-A | Alkenyl homopiperidine compound and preparation method thereof | 苏州大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-109963861-A | Novel trityl as protecting group agent | 积水医疗株式会社 | 2019-07-02 | — | — | CN | disclosed |
| CN-103841827-B | Small molecule compounds for controlling plant-and insect-pathogenic nematodes | 加利福尼亚技术学院 | 2017-06-09 | — | — | CN | disclosed |
| EP-2925725-A1 | NOVEL SELECTIVE ANDROGEN RECEPTOR MODULATORS | Pfizer Inc. (US) | 2015-10-07 | — | — | EP | disclosed |
| EP-2327727-B1 | Catalyst composition comprising shuttling agent for ethylene copolymer formation | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-07-22 | — | — | EP | disclosed |
| US-4849535-A | PROSTAGLANDINS | AJINOMOTO CO., INC. (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0078705-B1 | PROCESS FOR THE PREPARATION OF 1-HYDROXYLATED VITAMIN D COMPOUNDS | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) | 1988-04-27 | — | — | EP | disclosed |
| EP-0210929-A2 | Aromatic polycyclic derivatives, process for their preparation and their pharmaceutical and cosmetic use | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1987-02-04 | — | — | EP | disclosed |
| US-4554105-A | Process for the preparation of 1-hydroxylated vitamin D compounds | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) | 1985-11-19 | — | — | US | disclosed |
| EP-0078705-A1 | Process for the preparation of 1-hydroxylated vitamin D compounds | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) | 1983-05-11 | — | — | EP | disclosed |
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |