Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1538055 | 0.91 | — | — | |
| SCHEMBL619109 | 0.67 | TSHR (0.38) | TSHR | |
| SCHEMBL839012 | 0.67 | TSHR (0.38) | TSHR | |
| SCHEMBL15018256 | 0.67 | TSHR (0.38) | TSHR | |
| SCHEMBL838326 | 0.67 | — | — | |
| SCHEMBL12677819 | 0.67 | — | — | |
| SCHEMBL3481746 | 0.67 | — | — | |
| SCHEMBL12677627 | 0.67 | — | — | |
| SCHEMBL28595185 | 0.65 | TSHR (0.35) | TSHR | |
| SCHEMBL28593332 | 0.65 | TSHR (0.35) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200978-B1 | FOR PREVENTING OR TREATING INFLAMMATORY DISEASES SUCH AS ARTHRITIS, PSORIASIS, ASTHMA, OR INFLAMMATORY BOWEL DISEASE, DISORDERS OF RESPIRATORY FUNCTION, GASTROINTESTINAL DISORDERS SUCH AS FUNCTIONAL BOWEL DISEASE, AS ANALGESICS | PFIZER INC. | 2001-03-13 | — | — | US | disclosed |