SCHEMBL15380684

SCHEMBL15380684

CC(C)(C)O[SiH2]CCCN(CC1CCCO1)CC1CCCO1

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
LMNA P02545 3/20 0.33
MAPT P10636 1/20 0.33
POLB P06746 1/20 0.31
KDM4E B2RXH2 1/20 0.30
RORC P51449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15380093 0.88 ALDH1A1 (0.39) ALDH1A1LMNAMAPTRORC
SCHEMBL15379272 0.81 ALDH1A1 (0.38) ALDH1A1LMNAMAPTPOLBRORC
SCHEMBL15380616 0.78 ALDH1A1 (0.36) ALDH1A1LMNAMAPT
SCHEMBL15380443 0.77
SCHEMBL15380092 0.76 ALDH1A1 (0.34) ALDH1A1LMNAMAPTKDM4E
SCHEMBL614663 0.73 ALDH1A1 (0.42) ALDH1A1LMNAMAPTPOLB
SCHEMBL613960 0.73 ALDH1A1 (0.42) ALDH1A1LMNAMAPTPOLB
SCHEMBL9776559 0.73
SCHEMBL614664 0.70 ALDH1A1 (0.40) ALDH1A1LMNAMAPTPOLBKDM4E
SCHEMBL613916 0.70 ALDH1A1 (0.40) ALDH1A1LMNAMAPTPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10189987-B2 Pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-01-29 US disclosed
EP-3064546-B1 PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-08-29 EP disclosed
US-9932460-B2 Rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2018-04-03 US disclosed
US-9845385-B2 Rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-12-19 US disclosed
US-20160264772-A1 PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-09-15 US disclosed
EP-2674457-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2016-09-14 EP disclosed
EP-3064546-A1 PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2016-09-07 EP disclosed
EP-2708576-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2016-08-24 EP disclosed
EP-2671916-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2016-05-25 EP disclosed
US-9315647-B2 Rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-04-19 US disclosed
EP-2708576-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-03-19 EP disclosed
EP-2703443-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-03-05 EP disclosed
EP-2700671-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-02-26 EP disclosed
US-20140018490-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-01-16 US disclosed
US-20130345337-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-12-26 US disclosed
US-20130338296-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-12-19 US disclosed
EP-2674457-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2013-12-18 EP disclosed
EP-2671916-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2013-12-11 EP disclosed
US-20130310512-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-11-21 US disclosed
US-20130303679-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-11-14 US disclosed