Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 14/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 13/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11933388 | 0.95 | CDK9 (0.38) | CDK9CCNT1L3MBTL1PDE5AHDAC1 | |
| SCHEMBL15381760 | 0.95 | CDK9 (0.35) | CDK9CCNT1L3MBTL1PDE5AHDAC1 | |
| SCHEMBL11938888 | 0.93 | FFAR4 (0.34) | CDK9CCNT1L3MBTL1PDE5AHDAC1 | |
| SCHEMBL11939277 | 0.91 | CDK9 (0.33) | CDK9CCNT1PDE5AHDAC1HDAC6 | |
| SCHEMBL11933389 | 0.89 | CDK9 (0.37) | CDK9CCNT1L3MBTL1 | |
| SCHEMBL11933390 | 0.89 | CDK9 (0.37) | CDK9CCNT1L3MBTL1 | |
| SCHEMBL15381543 | 0.89 | CDK9 (0.39) | CDK9CCNT1PDE5AHDAC1HDAC6 | |
| SCHEMBL15381568 | 0.86 | PDE5A (0.40) | CDK9CCNT1PDE5AHDAC1HDAC6 | |
| SCHEMBL15381714 | 0.85 | CDK9 (0.36) | CDK9CCNT1PDE5AHDAC1HDAC6 | |
| SCHEMBL15381758 | 0.85 | CDK9 (0.36) | CDK9CCNT1PDE5AHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580147-B2 | Liquid crystal compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-11-12 | — | — | US | disclosed |