Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP2CA | P67775 | 7/20 | 0.90 |
| ▸ | PPP5C | P53041 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.72 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.63 |
| ▸ | PTPA | Q15257 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15381934 | 0.95 | PPP2CA (1.00) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL889288 | 0.94 | PPP2CA (0.80) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL15444945 | 0.91 | PPP2CA (0.90) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL15381940 | 0.91 | PPP2CA (0.90) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL15444944 | 0.91 | PPP2CA (0.90) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL15381941 | 0.90 | PPP2CA (0.90) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL889296 | 0.89 | PPP2CA (0.89) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL15444943 | 0.87 | PPP2CA (0.86) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL15381938 | 0.87 | PPP2CA (0.90) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL15444941 | 0.87 | PPP2CA (0.85) | PPP2CAPPP5CALDH1A1THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637684-B2 | Tautomycetin and tautomycetin analog biosynthesis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-01-28 | — | — | US | disclosed |
| US-8580977-B2 | Tautomycetin and tautomycetin analog biosynthesis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-11-12 | — | — | US | disclosed |