Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 15/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.66 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.66 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1770178 | 1.00 | ADRB3 (0.66) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| SCHEMBL10085311 | 1.00 | ADRB3 (0.66) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| SCHEMBL5458218 | 1.00 | ADRB3 (0.66) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| SCHEMBL364457 | 1.00 | ADRB3 (0.66) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| SCHEMBL7160000 | 1.00 | ADRB3 (0.66) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| SCHEMBL1592821 | 1.00 | ADRB3 (0.66) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7492283 | 0.99 | ADRB3 (0.65) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7487214 | 0.99 | ADRB3 (0.65) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7489762 | 0.99 | ADRB3 (0.65) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7488236 | 0.99 | ADRB3 (0.65) | ADRB3ADRB2ADRB1ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582709-B1 | AZOLOPYRIDIN-3-ONE DERIVATIVES AS INHIBITORS OF LIPASES AND PHOSPHOLIPASES | SANOFI SA (FR) | 2018-01-24 | — | — | EP | disclosed |
| EP-2470552-B1 | NOVEL CRYSTALLINE HETEROAROMATIC FLUOROGLYCOSIDE HYDRATES, PHARMACEUTICALS COMPRISING THESE COMPOUNDS AND THEIR USE | SANOFI SA (FR) | 2013-11-13 | — | — | EP | disclosed |