Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 15/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.66 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.66 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15382678 | 1.00 | ADRB3 (0.66) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| SCHEMBL1770178 | 1.00 | ADRB3 (0.66) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| SCHEMBL10085311 | 1.00 | ADRB3 (0.66) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| SCHEMBL364457 | 1.00 | ADRB3 (0.66) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| SCHEMBL7160000 | 1.00 | ADRB3 (0.66) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| SCHEMBL1592821 | 1.00 | ADRB3 (0.66) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7492283 | 0.99 | ADRB3 (0.65) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7487214 | 0.99 | ADRB3 (0.65) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7489762 | 0.99 | ADRB3 (0.65) | ADRB3ADRB2ADRB1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7488236 | 0.99 | ADRB3 (0.65) | ADRB3ADRB2ADRB1ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078181-A1 | Use of a beta-3-agonist for the treatment of patients with spinal cord injury and suffering from renal and bladder complaints | MICHEL MARTIN C | 2007-04-05 | — | — | US | disclosed |
| US-20060084700-A1 | Use of a beta-3 agonist for the treatment of disorders of the prostate and of the lower urogenital tract | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084700-A1 | Use of a beta-3 agonist for the treatment of disorders of the prostate and of the lower urogenital tract | ADRB3, ADRB2, ADRB1 | ADRB3 1/4885ADRB2 2/4885ADRB1 3/4885 |
| US-20070078181-A1 | Use of a beta-3-agonist for the treatment of patients with spinal cord injury and suffering from renal and bladder complaints | ADRB3, ADRB2, ADRB1 | ADRB3 1/4885ADRB2 2/4885ADRB1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.