Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL14333845 | 1.00 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3446226 | 1.00 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL17422 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1526184 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL30145601 | 0.94 | — | — | |
| Bicarbonate SCHEMBL2947807 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL15401810 | 0.89 | — | — | |
| Bicarbonate SCHEMBL1491908 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL16341225 | 0.89 | CA4 (0.55) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9624862 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2821223-B1 | SURFACE-COATED ALUMINUM AND ZINC PLATED STEEL SHEET AND METHOD OF PREPARING SAME | NIPPON STEEL & SUMIKIN COATED SHEET CORP (JP) | 2017-09-13 | — | — | EP | disclosed |
| EP-2687566-B1 | USE OF AN AQUEOUS METAL SURFACE TREATMENT AGENT FOR LITHIUM ION SECONDARY CELL | KYORITSU CHEMICAL & CO LTD (JP) | 2017-04-19 | — | — | EP | disclosed |
| US-9550910-B2 | Aqueous metal surface treatment agent for lithium ion secondary battery | KYORITSU CHEMICAL & CO., LTD. (JP) | 2017-01-24 | — | — | US | disclosed |
| US-20160083608-A1 | AQUEOUS METAL SURFACE TREATMENT AGENT FOR LITHIUM ION SECONDARY BATTERY | KYORITSU CHEMICAL & CO., LTD. (JP) | 2016-03-24 | — | — | US | disclosed |
| US-9133346-B2 | Surface-coated aluminum and zinc plated steel sheet and method of preparing same | NIPPON STEEL & SUMIKIN COATED SHEET CORPORATION (JP) | 2015-09-15 | — | — | US | disclosed |
| US-20150044498-A1 | SURFACE-COATED ALUMINUM AND ZINC PLATED STEEL SHEET AND METHOD OF PREPARING SAME | NIPPON STEEL COATED SHEET CORPORATION (JP) | 2015-02-12 | — | — | US | disclosed |
| EP-2821223-A1 | SURFACE-COATED ALUMINUM-CONTAINING GALVANIZED STEEL SHEET AND METHOD FOR PRODUCING SAME | Nippon Steel & Sumikin Coated Sheet Corporation (JP) | 2015-01-07 | — | — | EP | disclosed |
| EP-2687566-A1 | AQUEOUS METAL SURFACE TREATMENT AGENT FOR LITHIUM ION SECONDARY CELL | Kyoritsu Chemical & Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |
| US-20140005314-A1 | AQUEOUS METAL SURFACE TREATMENT AGENT FOR LITHIUM ION SECONDARY BATTERY | THE NIPPON SYNTHETIC CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-01-02 | — | — | US | disclosed |