Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1526184 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL30145601 | 1.00 | — | — | |
| Bicarbonate SCHEMBL12500507 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14333845 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3748174 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3446226 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL15401807 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1491908 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL31265062 | 0.94 | — | — | |
| Bicarbonate SCHEMBL6541114 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7892 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122081917-A | Low-temperature quick-setting self-repairing chromium-free passivation solution and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-121801442-B | Wet-on-wet water-based automobile intermediate paint based on interface self-reinforcement and multi-network cooperation, and preparation method and application thereof | Shandong jiameitai New Material Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| EP-4743312-A1 | HEAT-SENSITIVE RECORDING MATERIAL | Koehler Innovation & Technology GmbH (DE) | 2026-05-20 | — | — | EP | claimed |
| CN-122034562-A | Manufacturing process of improved asphalt-coated wall painting | 北京玄工科技有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122013589-A | High-gloss coating for coated paper and preparation method thereof | 中山汉洲科技实业有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122007341-A | Silica sol investment precision casting process | 辽宁华沣精密金属有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122013596-A | Disposable hand-tearing garbage coil paper base formula and preparation method thereof | 江苏维宸复合材料有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122011962-A | Preparation method of cassava starch-waste syrup-vinasse protein composite formaldehyde-free binder | 张波 | 2026-05-12 | — | — | CN | claimed |
| US-12617983-B2 | Starch-based aqueous adhesive composition | BOSTIK SA (FR) | 2026-05-05 | — | — | US | claimed |
| US-12617120-B2 | Wood protecting methods and wood products produced with the methods | ORGANOWOOD AB (SE) | 2026-05-05 | — | — | US | claimed |
| EP-0021602-B1 | TREATMENT OF TIN PLATE SURFACES AGAINST SULPHIDE STAINING | MB GROUP PLC (GB) | 1984-03-14 | — | — | EP | claimed |
| US-4354900-A | Strengthened fiberous electrochemical cell diaphragm and a method for making | DIAMOND SHAMROCK CORPORATION (US) | 1982-10-19 | — | — | US | claimed |
| US-4328040-A | COATED WITH ZIRCONIUM PRECIPITATED FROM AN ALKALINE SUSPENSION OF ALKALI OR AMMONIUM ZIRCONYL CARBONATE COMPLEX | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-04 | — | — | US | claimed |
| US-4294726-A | Catalyst for the purification of exhaust gases of internal combustion engines | DEUTSCHE GOLD-UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1981-10-13 | — | — | US | claimed |
| US-4294627-A | STAIN RESISTANT COATING FROM ZIRCONIUM ACETATE OR AMMONIUM ZIRCONIUM CARBONATE | METAL BOX LIMITED (GB) | 1981-10-13 | — | — | US | claimed |
| EP-0021602-A1 | Treatment of tin plate surfaces against sulphide staining | MB GROUP PLC (GB) | 1981-01-07 | — | — | EP | claimed |
| US-4201594-A | ZIRCONIUM SALT-CONTAINING BINDER, GELATION-INDUCING MAGNESIA, GELATION DELAY COMPOUND; MOLDING, SINTERING | ZIRCONAL PROCESSES LIMITED (GB) | 1980-05-06 | — | — | US | claimed |
| US-4200672-A | Stable copper zirconium complex salt solutions for enhancing the resistance to rot of cotton fabrics | MAGNESIUM ELEKTRON INC. (US) | 1980-04-29 | — | — | US | claimed |
| US-4061720-A | Preparation of ammonium and potassium zirconium carbonates | MAGNESIUM ELEKTRON LIMITED (EN) | 1977-12-06 | — | — | US | claimed |
| US-4013595-A | Non-flammable rug cleaning composition | S. C. JOHNSON & SON, INC. (US) | 1977-03-22 | — | — | US | claimed |