SCHEMBL15410092

SCHEMBL15410092

Cc1cc(C)cc([Si](Cl)(c2cc([Si](C)(C)C)cc([Si](C)(C)C)c2)c2cc([Si](C)(C)C)cc([Si](C)(C)C)c2)c1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32
NOTUM Q6P988 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12817142 1.00 ALDH1A1 (0.32) ALDH1A1TSHRNOTUM
SCHEMBL12816700 1.00 ALDH1A1 (0.32) ALDH1A1TSHRNOTUM
SCHEMBL12817427 1.00 ALDH1A1 (0.32) ALDH1A1TSHRNOTUM
SCHEMBL12815146 0.98
SCHEMBL1314841 0.87 ALDH1A1 (0.40) ALDH1A1TSHRNOTUM
SCHEMBL12816050 0.87 TDP1 (0.32) ALDH1A1
SCHEMBL12817591 0.87
SCHEMBL12817564 0.86 NR1H2 (0.32)
SCHEMBL12818315 0.86 NR1H2 (0.32)
SCHEMBL12817110 0.86 MAPT (0.33) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8937195-B2 Method for producing the transition metal complex, catalyst for trimerization, method for producing 1-hexene, method for producing the substituted cyclopentadiene compound (1) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-20 US disclosed
US-20140018564-A1 METHOD FOR PRODUCING THE TRANSITION METAL COMPLEX, CATALYST FOR TRIMERIZATION, METHOD FOR PRODUCING 1-HEXENE, METHOD FOR PRODUCING THE SUBSTITUTED CYCLOPENTADIENE COMPOUND (1) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-16 US disclosed