Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15409988 | 0.86 | KDM4E (0.37) | S1PR1KDM4EALDH1A1TLR8TLR7 | |
| SCHEMBL15233019 | 0.82 | HDAC1 (0.41) | S1PR1TLR8TLR7HDAC3HDAC1 | |
| SCHEMBL14948664 | 0.78 | HRH3 (0.43) | KDM4EALDH1A1TLR8TLR7HDAC3 | |
| SCHEMBL17080226 | 0.76 | ATM (0.41) | S1PR1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL14189703 | 0.75 | HDAC3 (0.45) | S1PR1KDM4EALDH1A1TLR8TLR7 | |
| SCHEMBL16560329 | 0.75 | CCR1 (0.40) | KDM4EALDH1A1HDAC6 | |
| SCHEMBL14449087 | 0.75 | HDAC3 (0.37) | KDM4EALDH1A1TLR8TLR7HDAC3 | |
| SCHEMBL16639002 | 0.74 | TAAR1 (0.45) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL14945527 | 0.74 | ESR1 (0.34) | KDM4EALDH1A1TLR8TLR7 | |
| SCHEMBL13878887 | 0.74 | HTR2C (0.37) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871940-B2 | Unsymmetrical bisazides for chemoselective sequential ligation | The Florida State University Research Foundation, Inc. (US) | 2014-10-28 | — | — | US | disclosed |
| US-8871940-B2 | Unsymmetrical bisazides for chemoselective sequential ligation | The Florida State University Research Foundation, Inc. (US) | 2014-10-28 | — | — | US | disclosed |
| US-8871940-B2 | Unsymmetrical bisazides for chemoselective sequential ligation | The Florida State University Research Foundation, Inc. (US) | 2014-10-28 | — | — | US | disclosed |
| US-20140018541-A1 | UMSYMMETRICAL BISAZIDES FOR CHEMOSELECTIVE SEQUENTIAL LIGATION | The Florida State University Research Foundation, Inc. (US) | 2014-01-16 | — | — | US | disclosed |
| US-20140018541-A1 | UMSYMMETRICAL BISAZIDES FOR CHEMOSELECTIVE SEQUENTIAL LIGATION | The Florida State University Research Foundation, Inc. (US) | 2014-01-16 | — | — | US | disclosed |
| US-20140018541-A1 | UMSYMMETRICAL BISAZIDES FOR CHEMOSELECTIVE SEQUENTIAL LIGATION | The Florida State University Research Foundation, Inc. (US) | 2014-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018541-A1 | UMSYMMETRICAL BISAZIDES FOR CHEMOSELECTIVE SEQUENTIAL LIGATION | UTS2R, UMPS, UGP2 | S1PR1 2608/4885KDM4E 2732/4885ALDH1A1 414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.