SCHEMBL15411461

SCHEMBL15411461

CC1=C(C)C(C)C([SiH2]c2cccc(-c3cccc(-c4ccccc4)c3)c2-c2cccc(-c3ccccc3)c2)=C1C

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32
PTGER1 P34995 1/20 0.30
PTGER4 P35408 1/20 0.30
PTGER3 P43115 1/20 0.30
PTGER2 P43116 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15409119 0.92 HPRT1 (0.33)
SCHEMBL15410895 0.88 ENPP1 (0.34)
SCHEMBL15409918 0.84
SCHEMBL15411261 0.84 CYP1A1 (0.37) BRD4
SCHEMBL10317955 0.82 BRD4 (0.32) BRD4CREBBP
SCHEMBL15410994 0.80 ENPP1 (0.32)
SCHEMBL15410233 0.80 BRD4 (0.33) BRD4
SCHEMBL15409943 0.78 PTGS2 (0.33)
SCHEMBL15411465 0.78
SCHEMBL15411303 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8937195-B2 Method for producing the transition metal complex, catalyst for trimerization, method for producing 1-hexene, method for producing the substituted cyclopentadiene compound (1) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-20 US disclosed
US-20140018564-A1 METHOD FOR PRODUCING THE TRANSITION METAL COMPLEX, CATALYST FOR TRIMERIZATION, METHOD FOR PRODUCING 1-HEXENE, METHOD FOR PRODUCING THE SUBSTITUTED CYCLOPENTADIENE COMPOUND (1) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-16 US disclosed