Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | IDE | P14735 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | FGF1 | P05230 | 1/20 | 0.48 |
| ▸ | FGF2 | P09038 | 1/20 | 0.48 |
| ▸ | VEGFA | P15692 | 1/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.48 |
| ▸ | MDK | P21741 | 1/20 | 0.44 |
| ▸ | HLCS | P50747 | 3/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biotin SCHEMBL1270776 | 0.83 | TDP1 (0.72) | TDP1MAPK1MEN1ABL1LMNA | |
| Biotin SCHEMBL1270496 | 0.78 | TDP1 (0.61) | TDP1MAPK1MEN1ABL1LMNA | |
| Biotin SCHEMBL2510950 | 0.78 | TDP1 (0.61) | TDP1MAPK1MEN1ABL1LMNA | |
| SCHEMBL9441198 | 0.75 | MAPK1 (0.48) | MAPK1 | |
| Biotin SCHEMBL6930604 | 0.75 | TDP1 (0.97) | TDP1MAPK1MEN1ABL1LMNA | |
| SCHEMBL42791 | 0.75 | MAPK1 (0.64) | MAPK1LMNA | |
| SCHEMBL22163862 | 0.75 | MAPK1 (0.64) | MAPK1LMNA | |
| SCHEMBL20533512 | 0.75 | MAPK1 (0.64) | MAPK1LMNA | |
| SCHEMBL17184967 | 0.75 | MAPK1 (0.64) | MAPK1LMNA | |
| SCHEMBL16241536 | 0.75 | MAPK1 (0.64) | MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2885638-A2 | MOLECULAR NETS | Sevident, Inc. (US) | 2015-06-24 | — | — | EP | disclosed |
| WO-2014011673-A2 | MOLECULAR NETS | SEVIDENT, INC. (US) | 2014-01-16 | — | — | WO | disclosed |