Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1532369 | 0.90 | ALDH1A1 (0.46) | ALDH1A1CYP3A4ALOX15USP2HPGD | |
| SCHEMBL1682637 | 0.86 | ALDH1A1 (0.42) | ALDH1A1CYP3A4ALOX15USP2HPGD | |
| Tetraethylene Glycol SCHEMBL29170069 | 0.85 | KMT2A (0.42) | ALDH1A1HPGDTDP1TSHRMAPK1 | |
| SCHEMBL10783672 | 0.83 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRMAPK1KMT2A | |
| SCHEMBL2120536 | 0.83 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRMAPK1KMT2A | |
| SCHEMBL10784800 | 0.83 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRMAPK1KMT2A | |
| SCHEMBL1845028 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRMAPK1KMT2A | |
| SCHEMBL8906051 | 0.81 | ALDH1A1 (0.41) | ALDH1A1CYP3A4ALOX15USP2HPGD | |
| SCHEMBL20324516 | 0.79 | ALDH1A1 (0.40) | ALDH1A1CYP3A4ALOX15USP2HPGD | |
| SCHEMBL1532367 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11674135-B2 | DNA-encoded libraries having encoding oligonucleotide linkages not readable by polymerases | X-CHEM, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| EP-3851529-A1 | DNA-ENCODED LIBRARIES HAVING ENCODING OLIGONUCLEOTIDE LINKAGES NOT READABLE BY POLYMERASES | X-Chem, Inc. (US) | 2021-07-21 | — | — | EP | disclosed |
| EP-3392338-B1 | DNA-ENCODED LIBRARIES HAVING ENCODING OLIGONUCLEOTIDE LINKAGES NOT READABLE BY POLYMERASES | X CHEM INC (US) | 2020-12-09 | — | — | EP | disclosed |
| US-20200143903-A1 | METHODS FOR IDENTIFYING COMPOUNDS | MIDCAP FINANCIAL TRUST | 2020-05-07 | — | — | US | disclosed |
| EP-3612545-A1 | METHODS FOR IDENTIFYING COMPOUNDS | X-Chem, Inc. (US) | 2020-02-26 | — | — | EP | disclosed |
| WO-2018195134-A1 | METHODS FOR IDENTIFYING COMPOUNDS | X-CHEM, INC. (US) | 2018-10-25 | — | — | WO | disclosed |
| EP-3392338-A1 | DNA-ENCODED LIBRARIES HAVING ENCODING OLIGONUCLEOTIDE LINKAGES NOT READABLE BY POLYMERASES | X-Chem, Inc. (US) | 2018-10-24 | — | — | EP | disclosed |
| EP-2872680-B1 | DNA-ENCODED LIBRARIES HAVING ENCODING OLIGONUCLEOTIDE LINKAGES NOT READABLE BY POLYMERASES | X CHEM INC (US) | 2018-04-04 | — | — | EP | disclosed |
| US-20180002688-A1 | METHODS FOR TAGGING DNA-ENCODED LIBRARIES | X-CHEM, INC. (US) | 2018-01-04 | — | — | US | disclosed |
| EP-3240795-A1 | METHODS FOR TAGGING DNA-ENCODED LIBRARIES | X-Chem, Inc. (US) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016109423-A1 | METHODS FOR TAGGING DNA-ENCODED LIBRARIES | X-CHEM, INC. (US) | 2016-07-07 | — | — | WO | disclosed |
| US-20150211002-A1 | DNA-ENCODED LIBRARIES HAVING ENCODING OLIGONUCLEOTIDE LINKAGES NOT READABLE BY POLYMERASES | PHARMACEUTICAL PRODUCT DEVELOPMENT, LLC | 2015-07-30 | — | — | US | disclosed |
| EP-2872680-A1 | DNA-ENCODED LIBRARIES HAVING ENCODING OLIGONUCLEOTIDE LINKAGES NOT READABLE BY POLYMERASES | X-Chem, Inc. (US) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014012010-A1 | DNA-ENCODED LIBRARIES HAVING ENCODING OLIGONUCLEOTIDE LINKAGES NOT READABLE BY POLYMERASES | X-CHEM, INC. (US) | 2014-01-16 | — | — | WO | disclosed |