Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 4/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 5/20 | 0.42 |
| ▸ | CTSK | P43235 | 5/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15414703 | 1.00 | ALDH1A1 (0.52) | ALDH1A1ACEPPARAPPARGITGB3 | |
| SCHEMBL18918283 | 0.91 | ALDH1A1 (0.48) | ALDH1A1ACEPPARAPPARGBCL2 | |
| SCHEMBL18918284 | 0.91 | ALDH1A1 (0.48) | ALDH1A1ACEPPARAPPARGBCL2 | |
| SCHEMBL7515400 | 0.88 | ALDH1A1 (0.67) | ALDH1A1ACEPPARAPPARGITGB3 | |
| SCHEMBL27292224 | 0.88 | ALDH1A1 (0.67) | ALDH1A1ACEPPARAPPARGITGB3 | |
| SCHEMBL28503691 | 0.87 | ALDH1A1 (0.55) | ALDH1A1ACEPPARAPPARGITGB3 | |
| SCHEMBL18925550 | 0.86 | ALDH1A1 (0.41) | ALDH1A1ACEPPARAPPARGBCL2 | |
| SCHEMBL18918272 | 0.86 | ALDH1A1 (0.41) | ALDH1A1ACEPPARAPPARGBCL2 | |
| SCHEMBL19473311 | 0.86 | ALDH1A1 (0.41) | ALDH1A1ACEPPARAPPARGBCL2 | |
| SCHEMBL28070912 | 0.86 | ACE (0.49) | ALDH1A1ACEPPARAPPARGITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834406-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-12-05 | — | — | US | disclosed |
| US-11767294-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-09-26 | — | — | US | disclosed |
| EP-3210627-B1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO LTD (CN) | 2022-12-21 | — | — | EP | disclosed |
| EP-2872157-B1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO LTD (CN) | 2020-01-22 | — | — | EP | disclosed |
| US-20190330149-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-10-31 | — | — | US | disclosed |
| US-10399941-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-09-03 | — | — | US | disclosed |
| EP-3348280-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | Hangzhou Dac Biotech Co., Ltd (CN) | 2018-07-18 | — | — | EP | disclosed |
| US-20180021448-A9 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2018-01-25 | — | — | US | disclosed |
| US-20170296663-A1 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2017-10-19 | — | — | US | disclosed |
| EP-3210627-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | Hangzhou Dac Biotech Co., Ltd (CN) | 2017-08-30 | — | — | EP | disclosed |
| US-20170157262-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2017-06-08 | — | — | US | disclosed |
| US-20170157262-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2017-06-08 | — | — | US | disclosed |
| US-20170157262-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2017-06-08 | — | — | US | disclosed |
| EP-2872157-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | Hangzhou Dac Biotech Co., Ltd (CN) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014009774-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2014-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330149-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | CD4, CD2, CD47 | ALDH1A1 3045/4885ACE 4721/4885PPARA 4715/4885 |
| US-10399941-B2 | Conjugates of cell binding molecules with cytotoxic agents | CD4, CD2, CD47 | ALDH1A1 3045/4885ACE 4721/4885PPARA 4715/4885 |
| US-20170157262-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | CD4, CD2, CD47 | ALDH1A1 3672/4885ACE 4787/4885PPARA 4754/4885 |
| US-11767294-B2 | Conjugates of cell binding molecules with cytotoxic agents | CD4, CD2, CD47 | ALDH1A1 3045/4885ACE 4721/4885PPARA 4715/4885 |
| US-20180021448-A9 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | CD4, CD2, CD47 | ALDH1A1 3045/4885ACE 4721/4885PPARA 4715/4885 |
| US-20170296663-A1 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | CD4, CD2, CD47 | ALDH1A1 3045/4885ACE 4721/4885PPARA 4715/4885 |
| US-11834406-B2 | Conjugates of cell binding molecules with cytotoxic agents | CD4, CD2, CD47 | ALDH1A1 3232/4885ACE 4747/4885PPARA 4696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.