Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D known ✓ | P28221 | 2/20 | 0.33 |
| ▸ | ADRA1A known ✓ | P35348 | 2/20 | 0.33 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D known ✓ | P25100 | 1/20 | 0.33 |
| ▸ | HTR1B known ✓ | P28222 | 1/20 | 0.33 |
| ▸ | ADRA1B known ✓ | P35368 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29839612 | 0.98 | AR (0.41) | ARKIF11ALDH1A1HPGDALOX15 | |
| SCHEMBL295096 | 0.98 | AR (0.41) | ARKIF11ALDH1A1HPGDALOX15 | |
| SCHEMBL20994195 | 0.87 | AR (0.41) | ARKIF11ALDH1A1MEN1MAPT | |
| SCHEMBL568588 | 0.81 | NOS3 (0.39) | ARIDO1MEN1KMT2ANOS3 | |
| SCHEMBL218725 | 0.81 | AR (0.45) | ARIDO1MEN1KMT2ANOS3 | |
| SCHEMBL14636523 | 0.81 | NOS3 (0.39) | ARIDO1NOS3NOS2HDAC8 | |
| SCHEMBL30847943 | 0.81 | AR (0.45) | ARIDO1MEN1KMT2ANOS3 | |
| SCHEMBL22140291 | 0.79 | AR (0.41) | ARALDH1A1HPGDTDP1IDO1 | |
| Hydrochloric Acid SCHEMBL19029428 | 0.79 | NOS3 (0.38) | ARIDO1NOS3NOS2 | |
| SCHEMBL27145090 | 0.78 | AR (0.37) | ARHSD17B10IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150171351-A1 | LIGHT-EMITTING COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2015-06-18 | — | — | US | disclosed |
| WO-2014009716-A1 | LIGHT-EMITTING COMPOUND | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2014-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150171351-A1 | LIGHT-EMITTING COMPOUND | NR2E3, MC1R, GALR1 | HTR1D 137/4885ADRA1A 80/4885ADRA2A 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.