SCHEMBL15414829

SCHEMBL15414829

CC(C)CC(=O)ONc1cccc(CN(Cc2ccc(-n3cccn3)cc2)S(=O)(=O)c2cccnc2)n1

nearest known ligand 0.74

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGER2 P43116 20/20 0.74
PTGER4 P35408 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15412431 0.90 PTGER2 (0.75) PTGER2PTGER4
Omidenepag Isopropyl SCHEMBL30434740 0.85 PTGER2 (1.00) PTGER2PTGER4
Omidenepag Isopropyl SCHEMBL29375346 0.85 PTGER2 (1.00) PTGER2PTGER4
Omidenepag Isopropyl SCHEMBL15414827 0.85 PTGER2 (1.00) PTGER2PTGER4
SCHEMBL533446 0.85 PTGER2 (0.78) PTGER2PTGER4
SCHEMBL16896244 0.84 PTGER2 (0.79) PTGER2PTGER4
SCHEMBL11026029 0.84 PTGER2 (0.76) PTGER2PTGER4
SCHEMBL22364205 0.84 PTGER2 (0.81) PTGER2PTGER4
Omidenepag SCHEMBL30433956 0.83 PTGER2 (1.00) PTGER2PTGER4
Omidenepag SCHEMBL533245 0.83 PTGER2 (1.00) PTGER2PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105828818-A Pharmaceutical Composition Containing Pyridylamino Acetic Acid Compound 参天制药株式会社 2016-08-03 CN disclosed
WO-2015105144-A1 PHARMACEUTICAL PREPARATION INCLUDING PYRIDYLAMINO ACETIC ACID COMPOUND 参天製薬株式会社 2015-07-16 WO disclosed
WO-2015105135-A1 PHARMACEUTICAL COMPOSITION CONTAINING PYRIDYLAMINO ACETIC ACID COMPOUND 参天製薬株式会社 2015-07-16 WO disclosed
WO-2014010654-A3 SULFONAMIDE COMPOUND COMBINATION 参天製薬株式会社 (JP) 2014-03-06 WO disclosed
WO-2014010654-A2 SULFONAMIDE COMPOUND COMBINATION 参天製薬株式会社 (JP) 2014-01-16 WO disclosed