Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 18/20 | 0.55 |
| ▸ | PGR | P06401 | 17/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 8/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12904794 | 0.90 | AR (0.68) | ARPGRNR3C2CYP19A1 | |
| SCHEMBL15417487 | 0.88 | AR (0.56) | ARPGRNR3C2CYP19A1 | |
| SCHEMBL12904809 | 0.87 | PGR (0.54) | ARPGRNR3C2CYP19A1 | |
| SCHEMBL16715979 | 0.82 | AR (0.62) | ARPGRNR3C2CYP19A1 | |
| SCHEMBL15417401 | 0.82 | AR (0.50) | ARPGRNR3C2CYP19A1 | |
| SCHEMBL12942855 | 0.81 | PGR (0.60) | ARPGRNR3C2CYP19A1 | |
| SCHEMBL15417407 | 0.81 | AR (0.52) | ARPGRNR3C2 | |
| SCHEMBL15417532 | 0.79 | AR (0.52) | ARPGRNR3C2 | |
| SCHEMBL12998919 | 0.79 | PGR (0.83) | ARPGRNR3C2CYP19A1 | |
| SCHEMBL15417475 | 0.79 | AR (0.36) | ARPGRNR3C2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623850-B2 | 15, 16-methylene-17-(1′-propenyl)-17,3′-oxidoestra-4-en-3-one derivative, use thereof, and medicament containing said derivative | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-07 | — | — | US | disclosed |