SCHEMBL15417604

SCHEMBL15417604

COC(=O)c1cc(C(=O)OC)cc(-c2nc(-c3ccccc3O)nc(-c3ccccc3O)n2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.55
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
NPSR1 Q6W5P4 2/20 0.55
POLB P06746 2/20 0.55
GAA P10253 3/20 0.53
HPGD P15428 3/20 0.53
ALDH1A1 P00352 2/20 0.53
KDM4A O75164 1/20 0.51
TSHR P16473 3/20 0.48
ADORA2A P29274 2/20 0.48
ALOX15 P16050 2/20 0.48
ADORA3 P0DMS8 1/20 0.48
ADORA2B P29275 1/20 0.48
ADORA1 P30542 1/20 0.48
EGFR P00533 1/20 0.47
MAPK1 P28482 1/20 0.46
LMNA P02545 3/20 0.45
KDM4E B2RXH2 2/20 0.45
XDH P47989 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9608510 0.92 MAPT (0.54) MAPTKMT2AMEN1NPSR1POLB
SCHEMBL9608524 0.91 KMT2A (0.50) MAPTKMT2AMEN1NPSR1POLB
SCHEMBL9608487 0.89 MEN1 (0.60) MAPTKMT2AMEN1NPSR1POLB
SCHEMBL9608519 0.87 MAPT (0.47) MAPTKMT2AMEN1NPSR1POLB
SCHEMBL9609235 0.87 NOTUM (0.48) MAPTKMT2AMEN1NPSR1POLB
SCHEMBL9609340 0.87 MEN1 (0.47) MAPTKMT2AMEN1NPSR1POLB
SCHEMBL9608388 0.87 MAPT (0.60) MAPTKMT2AMEN1NPSR1POLB
SCHEMBL15910001 0.87 MAPT (0.60) MAPTKMT2AMEN1NPSR1POLB
SCHEMBL9609316 0.85 MAPT (0.48) MAPTKMT2AMEN1NPSR1POLB
SCHEMBL9608537 0.85 MEN1 (0.57) MAPTKMT2AMEN1NPSR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2460799-B1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORP (JP) 2018-05-02 EP disclosed
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed