Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29206223 | 1.00 | SLC6A4 (0.54) | SLC6A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL10417448 | 0.98 | SLC6A4 (0.53) | SLC6A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL10290344 | 0.92 | CHRM2 (0.47) | SLC6A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL24575856 | 0.91 | CHRM2 (0.58) | SLC6A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL23028119 | 0.91 | CHRM2 (0.58) | SLC6A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL14086800 | 0.88 | SLC6A4 (0.42) | SLC6A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL22390592 | 0.86 | LMNA (0.43) | SLC6A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL11462522 | 0.85 | MEN1 (0.43) | SLC6A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL20214875 | 0.84 | CHRM2 (0.51) | SLC6A4CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL8493304 | 0.84 | SLC6A4 (0.40) | SLC6A4CHRM2HTR1AADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623893-B2 | Pyridino-pyridinone derivatives, preparation and therapeutic use thereof | SANOFI (FR) | 2014-01-07 | — | — | US | disclosed |