Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16459588 | 0.93 | REN (0.48) | RENUSP30 | |
| SCHEMBL15435778 | 0.93 | REN (0.48) | RENUSP30 | |
| SCHEMBL16471525 | 0.92 | REN (0.47) | RENUSP30JAK2JAK1 | |
| SCHEMBL12526795 | 0.91 | REN (0.48) | RENUSP30 | |
| SCHEMBL16471560 | 0.84 | REN (0.68) | REN | |
| SCHEMBL16471562 | 0.84 | REN (0.69) | REN | |
| SCHEMBL16471568 | 0.83 | REN (0.69) | REN | |
| SCHEMBL15435779 | 0.82 | REN (0.41) | RENUSP30 | |
| SCHEMBL15435780 | 0.82 | REN (0.58) | REN | |
| SCHEMBL16471583 | 0.82 | REN (0.58) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687518-B1 | NITROGEN-CONTAINING SATURATED HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-11-01 | — | — | EP | disclosed |
| EP-2687518-A1 | NITROGEN-CONTAINING SATURATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2014-01-22 | — | — | EP | disclosed |