Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3778417 | 0.74 | CYP2C9 (0.56) | CYP2C9NR4A2NPC1RAB9A | |
| SCHEMBL3366348 | 0.74 | CYP2C9 (0.73) | CYP2C9NR4A2NPC1RAB9AEGLN1 | |
| SCHEMBL3367862 | 0.73 | CYP2C9 (0.69) | CYP2C9NR4A2NPC1RAB9AEGLN1 | |
| SCHEMBL3767306 | 0.73 | NR4A2 (0.65) | CYP2C9NR4A2NPC1RAB9AEGLN1 | |
| SCHEMBL3765093 | 0.72 | NR4A2 (0.67) | CYP2C9NR4A2NPC1RAB9AEGLN1 | |
| SCHEMBL2485519 | 0.72 | RAB9A (0.68) | CYP2C9NR4A2NPC1RAB9AEGLN1 | |
| SCHEMBL3767001 | 0.71 | NR4A2 (0.72) | CYP2C9NR4A2NPC1RAB9AEGLN1 | |
| SCHEMBL3368461 | 0.71 | NPC1 (0.70) | CYP2C9NR4A2NPC1RAB9AEGLN1 | |
| SCHEMBL3772210 | 0.70 | NR4A2 (0.71) | CYP2C9NR4A2NPC1RAB9AEGLN1 | |
| SCHEMBL3367873 | 0.70 | NPC1 (0.62) | CYP2C9NR4A2NPC1RAB9AEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225240-B1 | Derivatives of 6-heterocyclic-imidazo[1,2-a]pyridine-2-carboxamides, preparation thereof and therapeutic application thereof | SANOFI SA (FR) | 2014-01-22 | — | — | EP | disclosed |