Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1530321 | 0.81 | CRBN (0.63) | CRBNEPHX2NR1H4PPARGGAA | |
| SCHEMBL1530443 | 0.79 | DDB1 (0.38) | CRBNEPHX2NR1H4PPARGGAA | |
| SCHEMBL2915590 | 0.79 | GAA (0.36) | EPHX2NR1H4PPARGGAAHPGD | |
| SCHEMBL1530231 | 0.74 | CRBN (0.66) | CRBNALDH1A1BRPF1 | |
| SCHEMBL1530745 | 0.73 | CRBN (0.66) | CRBNALDH1A1 | |
| SCHEMBL478823 | 0.73 | CRBN (0.63) | CRBN | |
| SCHEMBL1530701 | 0.71 | CRBN (0.64) | CRBNALDH1A1KAT2B | |
| SCHEMBL1530593 | 0.71 | CRBN (0.43) | CRBN | |
| SCHEMBL1531039 | 0.71 | CRBN (0.63) | CRBN | |
| SCHEMBL15419007 | 0.70 | CRBN (0.62) | CRBNSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-B1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBVIE BAHAMAS LTD (BS) | 2014-01-22 | — | — | EP | claimed |