Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10492237 | 0.94 | LMNA (0.42) | LMNATDP1EGFRHDAC3CNR1 | |
| SCHEMBL8369796 | 0.94 | LMNA (0.42) | LMNATDP1EGFRHDAC3CNR1 | |
| SCHEMBL8369798 | 0.94 | LMNA (0.42) | LMNATDP1EGFRHDAC3CNR1 | |
| SCHEMBL8019898 | 0.92 | TDP1 (0.44) | LMNATDP1EGFRCNR1MAPT | |
| SCHEMBL3499907 | 0.92 | TDP1 (0.44) | LMNATDP1EGFRCNR1MAPT | |
| SCHEMBL8019896 | 0.92 | TDP1 (0.44) | LMNATDP1EGFRCNR1MAPT | |
| SCHEMBL11424521 | 0.87 | MAOB (0.39) | LMNATDP1MAOBRELA | |
| SCHEMBL4076697 | 0.87 | MAOB (0.39) | LMNATDP1MAOBRELA | |
| SCHEMBL1509680 | 0.78 | MAOB (0.42) | LMNAMAOBRELA | |
| SCHEMBL5083636 | 0.78 | MAOB (0.42) | LMNAMAOBRELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483326-B1 | COMPOSITION COMPRISING MIXED ELASTOMERS AND SUPRAMOLECULAR POLYMERS | ARKEMA FRANCE (FR) | 2014-01-22 | — | — | EP | claimed |