Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1788091 | 1.00 | MEN1 (0.51) | MEN1KMT2AKDM4ETDP1TSHR | |
| SCHEMBL15673155 | 0.86 | KMT2A (0.70) | MEN1KMT2AKDM4ETDP1TSHR | |
| SCHEMBL11309469 | 0.84 | MEN1 (0.72) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL10697747 | 0.84 | MEN1 (0.72) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL11309467 | 0.84 | MEN1 (0.72) | MEN1KMT2AKDM4ETDP1ALDH1A1 | |
| SCHEMBL2532167 | 0.83 | KDM4E (0.53) | MEN1KMT2AKDM4ETDP1TSHR | |
| SCHEMBL8702266 | 0.83 | KDM4E (0.53) | MEN1KMT2AKDM4ETDP1TSHR | |
| SCHEMBL7067850 | 0.83 | CYP1A1 (0.45) | KDM4ECYP1A2NPSR1 | |
| SCHEMBL9487608 | 0.82 | MEN1 (0.51) | MEN1KMT2AKDM4ETDP1TSHR | |
| SCHEMBL9487600 | 0.82 | MEN1 (0.51) | MEN1KMT2AKDM4ETDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648202-B2 | Bis(perfluoroalkyl)phosphinous acids and derivatives and use thereof | MERCK PATENT GMBH (DE) | 2014-02-11 | — | — | US | disclosed |
| EP-2303902-B1 | BIS(PERFLUORALKYL)PHOSPHINOUS ACIDS AND DERIVATES AND USE THEREOF | MERCK PATENT GMBH (DE) | 2013-08-21 | — | — | EP | disclosed |
| CN-102105477-A | Bis(perfluoralkyl)phosphinous acids and derivates and use thereof | MERCK PATENT GMBH | 2011-06-22 | — | — | CN | disclosed |
| US-20110124873-A1 | Bis(perfluoralkyl)phosphinous acids and derivatives and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-05-26 | — | — | US | disclosed |
| EP-2303902-A1 | BIS(PERFLUORALKYL)PHOSPHINOUS ACIDS AND DERIVATES AND USE THEREOF | Merck Patent GmbH (DE) | 2011-04-06 | — | — | EP | disclosed |
| WO-2010009818-A1 | BIS(PERFLUORALKYL)PHOSPHINOUS ACIDS AND DERIVATES AND USE THEREOF | MERCK PATENT GMBH (DE) | 2010-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124873-A1 | Bis(perfluoralkyl)phosphinous acids and derivatives and use thereof | PFKFB3, PFAS, PFKFB2 | MEN1 2111/4885KMT2A 3493/4885KDM4E 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.