SCHEMBL1542015

SCHEMBL1542015

FC(F)(F)C(F)(F)C(F)(F)P(Cl)(Cl)(Cl)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15546171 0.67 LMNA (0.30)
SCHEMBL2370655 0.67 LMNA (0.30)
Perflubutane SCHEMBL111514 0.61 LMNA (0.54)
Perflutren SCHEMBL1446805 0.61 LMNA (0.43)
Perflubutane SCHEMBL9051673 0.61 LMNA (0.54)
Perflutren SCHEMBL34348 0.61 LMNA (0.43)
Perflutren SCHEMBL23928389 0.59 LMNA (0.35)
SCHEMBL5622699 0.59
SCHEMBL20548486 0.57 LMNA (0.35)
SCHEMBL1542042 0.57 LMNA (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2303899-B1 PROCESS FOR PREPARING BIS(FLUOROALKYL)PHOSPHINIC ACID OR FLUOROALKYLPHOSPHONIC ACID MERCK PATENT GMBH (DE) 2014-09-24 EP disclosed
US-20110130589-A1 PROCESS FOR THE PREPARATION OF BIS(FLUOROALKYL)PHOSPHINIC ACID OR FLUOROALKYLPHOSPHONIC ACID MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-06-02 US disclosed
EP-2303899-A1 PROCESS FOR PREPARING BIS(FLUOROALKYL)PHOSPHINIC ACID OR FLUOROALKYLPHOSPHONIC ACID Merck Patent GmbH (DE) 2011-04-06 EP disclosed
WO-2010012359-A1 PROCESS FOR PREPARING BIS(FLUOROALKYL)PHOSPHINIC ACID OR FLUOROALKYLPHOSPHONIC ACID MERCK PATENT GMBH (DE) 2010-02-04 WO disclosed