Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.62 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536354 | 1.00 | FOLH1 (0.62) | FOLH1DPP4DPP8DPP9PTGS1 | |
| SCHEMBL210006 | 1.00 | FOLH1 (0.62) | FOLH1DPP4DPP8DPP9PTGS1 | |
| SCHEMBL15420941 | 1.00 | FOLH1 (0.62) | FOLH1DPP4DPP8DPP9PTGS1 | |
| SCHEMBL210315 | 1.00 | FOLH1 (0.62) | FOLH1DPP4DPP8DPP9PTGS1 | |
| SCHEMBL27611010 | 0.97 | FOLH1 (0.58) | FOLH1DPP4DPP8DPP9PTGS1 | |
| SCHEMBL27611015 | 0.97 | FOLH1 (0.58) | FOLH1DPP4DPP8DPP9PTGS1 | |
| SCHEMBL16770243 | 0.97 | FOLH1 (0.58) | FOLH1DPP4DPP8DPP9PTGS1 | |
| Glycine SCHEMBL343653 | 0.95 | FOLH1 (0.57) | FOLH1DPP4DPP8DPP9PTGS1 | |
| SCHEMBL9760353 | 0.95 | FOLH1 (0.61) | FOLH1DPP4DPP8DPP9PTGS1 | |
| SCHEMBL30382437 | 0.95 | FOLH1 (0.61) | FOLH1DPP4DPP8DPP9PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9532961-B2 | Method and kit for administering γ-glutamyl-D-cysteine for the prevention of reperfusion injury following ischemic stroke | ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE (US) | 2017-01-03 | — | — | US | disclosed |
| US-20160193167-A9 | METHOD AND KIT FOR ADMINISTERING GAMMA-GLUTAMYL-D-CYSTEINE FOR THE PREVENTION OF REPERFUSION INJURY FOLLOWING ISCHEMIC STROKE | ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE (US) | 2016-07-07 | — | — | US | disclosed |
| US-20140024715-A1 | METHOD AND KIT FOR ADMIINISTERING GAMMA-GLUTAMYL-D-CYSTEINE FOR THE PREVENTION OF REPERFUSION INJURY FOLLOWING ISCHEMIC STROKE | ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE (US) | 2014-01-23 | — | — | US | disclosed |