SCHEMBL536354

SCHEMBL536354

NC(CCC(=O)O)C(=O)NC(CS)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 4/20 0.62
DPP4 P27487 1/20 0.53
DPP8 Q6V1X1 1/20 0.53
DPP9 Q86TI2 1/20 0.53
PTGS1 P23219 1/20 0.52
GSTK1 Q9Y2Q3 1/20 0.52
GRM8 O00222 1/20 0.52
GRM6 O15303 1/20 0.52
GRIN2D O15399 1/20 0.52
GRIN3B O60391 1/20 0.52
GSR P00390 1/20 0.52
CYP1A2 P05177 1/20 0.52
GRIK1 P39086 1/20 0.52
GRM5 P41594 1/20 0.52
GRIA1 P42261 1/20 0.52
GRIA2 P42262 1/20 0.52
GRIA3 P42263 1/20 0.52
SLC1A3 P43003 1/20 0.52
SLC1A2 P43004 1/20 0.52
SLC1A1 P43005 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15420942 1.00 FOLH1 (0.62) FOLH1DPP4DPP8DPP9PTGS1
SCHEMBL210006 1.00 FOLH1 (0.62) FOLH1DPP4DPP8DPP9PTGS1
SCHEMBL15420941 1.00 FOLH1 (0.62) FOLH1DPP4DPP8DPP9PTGS1
SCHEMBL210315 1.00 FOLH1 (0.62) FOLH1DPP4DPP8DPP9PTGS1
SCHEMBL27611010 0.97 FOLH1 (0.58) FOLH1DPP4DPP8DPP9PTGS1
SCHEMBL27611015 0.97 FOLH1 (0.58) FOLH1DPP4DPP8DPP9PTGS1
SCHEMBL16770243 0.97 FOLH1 (0.58) FOLH1DPP4DPP8DPP9PTGS1
Glycine SCHEMBL343653 0.95 FOLH1 (0.57) FOLH1DPP4DPP8DPP9PTGS1
SCHEMBL9760353 0.95 FOLH1 (0.61) FOLH1DPP4DPP8DPP9PTGS1
SCHEMBL30382437 0.95 FOLH1 (0.61) FOLH1DPP4DPP8DPP9PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 952 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116769738-B Glutamyl cysteine synthetase mutant and application thereof in glutathione synthesis 江苏集萃工业生物技术研究所有限公司 2026-05-12 CN claimed
US-20250334558-A1 TOTAL HYDROGEN SULFIDE QUANTIFICATION CLEVELAND CLINIC FOUND (US) 2025-10-30 US claimed
EP-4622471-A1 BOVINE COLOSTRUM-DERIVED NUTRITIONAL SUPPLEMENTS AND USES THEREOF University of Maryland, Baltimore (US) 2025-10-01 EP claimed
EP-4608966-A1 YEAST COMPOSITIONS HAVING ANTIOXIDANT PROPERTIES DANSTAR FERMENT AG (CH) 2025-09-03 EP claimed
US-20250269072-A1 PROCESSES FOR PREPARING RADIOLABELLED CONJUGATES CENTENARY INST OF CANCER MEDICINE AND CELL BIOLOGY (AU) 2025-08-28 US claimed
US-20250228969-A1 GENE EDITING TO IMPROVE JOINT FUNCTION ORTHOBIO THERAPEUTICS, INC. 2025-07-17 US claimed
EP-4491702-A1 BIOLOGICAL ANTIOXIDANT FOR FRUIT JUICE AND FRUIT WINE, PREPARATION METHOD THEREFOR, AND USE THEREOF Angel Yeast Co., Ltd (CN) 2025-01-15 EP claimed
US-20240385183-A1 METABOLIC AND MICROBIAL BIOMARKERS FOR DETECTION OF PANCREATICOBILIARY CANCERS NORTHWESTERN UNIVERSITY 2024-11-21 US claimed
CN-118549609-A Method for researching action mechanism of Nrf2/ARE signal path on resveratrol for protecting dopaminergic nerve cells 东莞市松山湖中心医院(东莞市石龙人民医院、东莞市第三人民医院、东莞市心血管病研究所) 2024-08-27 CN claimed
EP-4416121-A1 PROCESSES FOR PREPARING RADIOLABELLED CONJUGATES Centenary Institute Of Cancer Medicine And Cell Biology (AU) 2024-08-21 EP claimed
EP-0648261-A1 A RETROVIRAL VECTOR CAPABLE OF TRANSDUCING THE ALDEHYDE DEHYDROGENASE-1 GENE AND USES OF SAID VECTOR THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1995-04-19 EP claimed
WO-1994023015-A1 A RETROVIRAL VECTOR CAPABLE OF TRANSDUCING THE ALDEHYDE DEHYDROGENASE-1 GENE AND USES OF SAID VECTOR THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1994-10-13 WO claimed
EP-0608217-A1 SOLUBLE AND STABLE SOURCES OF TYROSINE, CYSTEINE AND GLUTAMINE FOR TOTAL PARENTERAL NUTRITION RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1994-08-03 EP claimed
EP-0583367-A1 METHODS AND COMPOSITIONS FOR INHIBITING DEPOSIT FORMATION ON CONTACT LENSES ALLERGAN, INC. (US) 1994-02-23 EP claimed
EP-0608217-A4 SOLUBLE AND STABLE SOURCES OF TYROSINE, CYSTEINE AND GLUTAMINE FOR TOTAL PARENTERAL NUTRITION. RES CORP TECHNOLOGIES INC (US) 1993-12-06 EP claimed
WO-1992021049-A1 METHODS AND COMPOSITIONS FOR INHIBITING DEPOSIT FORMATION ON CONTACT LENSES ALLERGAN, INC. (US) 1992-11-26 WO claimed
WO-1991016067-A1 SOLUBLE AND STABLE SOURCES OF TYROSINE, CYSTEINE AND GLUTAMINE FOR TOTAL PARENTERAL NUTRITION RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-10-31 WO claimed
CN-1049598-A Alimentation composition KYOWA HAKKO KOGYO KK (JP) 1991-03-06 CN claimed
CN-1044660-A Biologically active whey protein composition, method for producing same and use of said composition GUSTAVO BOUNOUS (CA) 1990-08-15 CN claimed
EP-0375852-A1 Biologically active whey protein composition, a method for producing it and use of the composition IMMUNOTEC RESEARCH CORPORATION LTD. (CA) 1990-07-04 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250269072-A1 PROCESSES FOR PREPARING RADIOLABELLED CONJUGATES AS3MT, TP53, ANXA5 FOLH1 252/4885DPP4 3410/4885DPP8 3592/4885
US-20250228969-A1 GENE EDITING TO IMPROVE JOINT FUNCTION ROS1, SYVN1, ATF4 FOLH1 2842/4885DPP4 3243/4885DPP8 2451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.