Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.76 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14470092 | 0.90 | MEN1 (0.81) | MEN1KMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL14821411 | 0.86 | MEN1 (0.75) | MEN1KMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL14470115 | 0.86 | MEN1 (0.75) | MEN1KMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL5915300 | 0.86 | MEN1 (0.75) | MEN1KMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL3813872 | 0.86 | MEN1 (0.75) | MEN1KMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL17628468 | 0.82 | KMT2A (0.70) | MEN1KMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL14469937 | 0.81 | MEN1 (0.67) | MEN1KMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL31212433 | 0.81 | MEN1 (0.67) | MEN1KMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL31212426 | 0.81 | MEN1 (0.67) | MEN1KMT2AGAAHTTSMN1; SMN2 | |
| SCHEMBL31212429 | 0.81 | MEN1 (0.67) | MEN1KMT2AGAAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014012054-A1 | ALZHEIMER'S DISEASE ASSAY IN A LIVING PATENT | PAIN THERAPEUTICS, INC. (US) | 2014-01-16 | — | — | WO | disclosed |