SCHEMBL3813872

SCHEMBL3813872

Cc1ccc(S(=O)(=O)N2CCC(Cc3ccccc3)CC2)cc1

nearest known ligand 0.81

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.75
KMT2A Q03164 6/20 0.75
ALDH1A1 P00352 4/20 0.66
HSD17B10 Q99714 1/20 0.66
TSHR P16473 4/20 0.66
GAA P10253 3/20 0.66
HTT P42858 2/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
LMNA P02545 4/20 0.65
MAPT P10636 1/20 0.65
NPSR1 Q6W5P4 1/20 0.61
PKM P14618 1/20 0.59
POLB P06746 1/20 0.58
MAPK1 P28482 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14470092 0.90 MEN1 (0.81) MEN1KMT2AALDH1A1HSD17B10TSHR
SCHEMBL14821411 0.86 MEN1 (0.75) MEN1KMT2AALDH1A1HSD17B10TSHR
SCHEMBL14470115 0.86 MEN1 (0.75) MEN1KMT2AALDH1A1HSD17B10TSHR
SCHEMBL15423952 0.86 MEN1 (0.76) MEN1KMT2AALDH1A1HSD17B10TSHR
SCHEMBL5915300 0.86 MEN1 (0.75) MEN1KMT2AALDH1A1HSD17B10TSHR
SCHEMBL17628468 0.82 KMT2A (0.70) MEN1KMT2AALDH1A1HSD17B10TSHR
SCHEMBL13743135 0.82 MEN1 (0.58) MEN1KMT2AALDH1A1HSD17B10TSHR
SCHEMBL29025657 0.82 MEN1 (0.52) MEN1KMT2AALDH1A1HSD17B10TSHR
SCHEMBL10795112 0.81 MEN1 (0.56) MEN1KMT2AALDH1A1TSHRGAA
SCHEMBL14469937 0.81 MEN1 (0.67) MEN1KMT2AALDH1A1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116143688-B Preparation method of 3-piperidone compound 江南大学 2025-03-11 CN disclosed
CN-116143688-A Preparation method of 3-piperidone compound 江南大学 2023-05-23 CN disclosed
US-8263808-B2 Method for deprotecting aryl or alkyl sulfonamides of primary or secondary amines SIGNA CHEMISTRY, INC. (US) 2012-09-11 US disclosed
US-8263808-B2 Method for deprotecting aryl or alkyl sulfonamides of primary or secondary amines SIGNA CHEMISTRY, INC. (US) 2012-09-11 US disclosed
US-8263808-B2 Method for deprotecting aryl or alkyl sulfonamides of primary or secondary amines SIGNA CHEMISTRY, INC. (US) 2012-09-11 US disclosed
US-20090306391-A1 METHOD FOR DEPROTECTING ARYL OR ALKYL SULFONAMIDES OF PRIMARY OR SECONDARY AMINES SIGNA CHEMISTRY, LLC (US) 2009-12-10 US disclosed
US-20090306391-A1 METHOD FOR DEPROTECTING ARYL OR ALKYL SULFONAMIDES OF PRIMARY OR SECONDARY AMINES SIGNA CHEMISTRY, LLC (US) 2009-12-10 US disclosed
US-20090306391-A1 METHOD FOR DEPROTECTING ARYL OR ALKYL SULFONAMIDES OF PRIMARY OR SECONDARY AMINES SIGNA CHEMISTRY, LLC (US) 2009-12-10 US disclosed
EP-2035465-A2 METHOD FOR DEPROTECTING ARYL OR ALKYL SULFONAMIDES OF PRIMARY OR SECONDARY AMINES SIGNA CHEMISTRY LLC (US) 2009-03-18 EP disclosed
WO-2007095276-A2 METHOD FOR DEPROTECTING ARYL OR ALKYL SULFONAMIDES OF PRIMARY OR SECONDARY AMINES SIGNA CHEMISTRY, LLC (US) 2007-08-23 WO disclosed
US-7250444-B2 Pyrrole-based HMG-CoA reductase inhibitors PFIZER INC. (US) 2007-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090306391-A1 METHOD FOR DEPROTECTING ARYL OR ALKYL SULFONAMIDES OF PRIMARY OR SECONDARY AMINES ARSA, KCNJ1, SIK3 MEN1 2135/4885KMT2A 73/4885ALDH1A1 1195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.