SCHEMBL15426488

SCHEMBL15426488

Cc1ccc(SSc2ccc(Cl)nc2)cn1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
CYP2A6 P11509 1/20 0.36
DGAT1 O75907 2/20 0.36
PIK3CD O00329 1/20 0.34
NAPRT Q6XQN6 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10280707 0.87 PIK3CD (0.41) CYP2A6DGAT1PIK3CDNAPRTPOLB
SCHEMBL29978927 0.74
SCHEMBL1145839 0.74
SCHEMBL2894259 0.72
SCHEMBL21288402 0.70
SCHEMBL21321543 0.70
SCHEMBL1145837 0.70
SCHEMBL23833573 0.69 SMN1; SMN2 (0.41) DGAT1PIK3CDNAPRTPOLBSMN1; SMN2
SCHEMBL23845466 0.69 DGAT1 (0.37) DGAT1PIK3CDNAPRTPOLB
SCHEMBL23048494 0.69 MEN1 (0.38) LMNAKMT2AMEN1CYP2A6NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9392791-B2 Amide compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-19 US disclosed
US-9278983-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-08 US disclosed
US-20150336895-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-26 US disclosed
US-9156838-B2 Fused heterocyclic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-13 US disclosed
US-20150246911-A1 FUSED HETEROCYCLIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-09-03 US disclosed
US-20140364444-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-12-11 US disclosed
US-8853238-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-10-07 US disclosed
US-20140018373-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140018373-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF NR4A1, NR2C2, NR0B1 LMNA 1591/4885KMT2A 700/4885MEN1 767/4885
US-20150336895-A1 AMIDE COMPOUND AND USE THEREOF FOR PEST CONTROL C5, H1-3, H1-0 LMNA 3311/4885KMT2A 979/4885MEN1 2768/4885
US-20150246911-A1 FUSED HETEROCYCLIC COMPOUND NR4A1, NR4A3, NR4A2 LMNA 4096/4885KMT2A 1636/4885MEN1 1829/4885
US-20140364444-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL NR4A1, NR2C2, NR0B1 LMNA 1629/4885KMT2A 675/4885MEN1 795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.