Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAC2 | P15153 | 1/20 | 0.32 |
| ▸ | RAC3 | P60763 | 1/20 | 0.32 |
| ▸ | CDC42 | P60953 | 1/20 | 0.32 |
| ▸ | RAC1 | P63000 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16978543 | 0.96 | RAC2 (0.32) | RAC2RAC3CDC42RAC1KDM4E | |
| SCHEMBL783565 | 0.94 | MAPT (0.34) | KDM4EL3MBTL1ATMMAPTMAPK1 | |
| SCHEMBL17904180 | 0.93 | KDM4E (0.34) | KDM4EL3MBTL1ATMMAPTMAPK1 | |
| SCHEMBL15606733 | 0.93 | KDM4E (0.34) | RAC2RAC3CDC42RAC1KDM4E | |
| SCHEMBL15806102 | 0.92 | KDM4E (0.35) | KDM4EL3MBTL1ATM | |
| SCHEMBL15832139 | 0.92 | KDM4E (0.35) | KDM4EL3MBTL1ATM | |
| SCHEMBL16978556 | 0.92 | KDM4E (0.35) | KDM4EL3MBTL1ATM | |
| SCHEMBL16689524 | 0.92 | KDM4E (0.33) | RAC2RAC3CDC42RAC1KDM4E | |
| SCHEMBL16978573 | 0.92 | MAPT (0.33) | KDM4EL3MBTL1ATMMAPTMAPK1 | |
| SCHEMBL16978582 | 0.92 | MAPT (0.33) | KDM4EL3MBTL1ATMMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9385335-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2016-07-05 | — | — | US | disclosed |
| US-9385335-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2016-07-05 | — | — | US | disclosed |
| US-20140014940-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2014-01-16 | — | — | US | disclosed |
| US-20140014940-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2014-01-16 | — | — | US | disclosed |