Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 6/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 6/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 5/20 | 0.32 |
| ▸ | KCNJ8 | Q15842 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14970104 | 1.00 | MET (0.44) | METDRD5HTR2CHTR6ALDH1A1 | |
| SCHEMBL14969968 | 0.85 | MET (0.47) | METALDH1A1GAAKDM4EGLA | |
| SCHEMBL12649854 | 0.85 | MET (0.47) | METALDH1A1GAAKDM4EGLA | |
| SCHEMBL12649767 | 0.84 | MET (0.48) | METALDH1A1GAAMEN1MAPT | |
| SCHEMBL14956189 | 0.84 | MET (0.48) | METALDH1A1GAAMEN1MAPT | |
| SCHEMBL12649898 | 0.80 | MET (0.51) | METDRD5HTR2CHTR6ALDH1A1 | |
| SCHEMBL1769243 | 0.76 | MET (0.48) | METALDH1A1GAAMEN1MAPT | |
| SCHEMBL15426699 | 0.74 | MET (0.51) | METALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL562365 | 0.71 | MET (0.49) | METDRD5HTR2CHTR6ALDH1A1 | |
| SCHEMBL14970033 | 0.71 | MET (0.46) | METDRD5HTR2CHTR6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501700-B1 | Furopyridinyl-substituted 1,4-dihydropyridine derivatives and methods of use thereof | BAYER IP GMBH (DE) | 2014-01-15 | — | — | EP | disclosed |