SCHEMBL1542687

SCHEMBL1542687

CS(=O)(=O)c1ccccc1Br

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.62
CA2 P00918 3/20 0.62
CA4 P22748 2/20 0.62
CA6 P23280 2/20 0.62
PLCG1 P19174 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.44
RECQL P46063 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
AKR1B1 P15121 1/20 0.42
EDNRA P25101 2/20 0.41
EDNRB P24530 1/20 0.41
CA5A P35218 2/20 0.41
CA9 Q16790 2/20 0.41
LOX P28300 1/20 0.41
ALDH1A1 P00352 1/20 0.40
BCAT2 O15382 1/20 0.40
HSD11B1 P28845 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29890712 1.00 CA1 (0.62) CA1CA2CA4CA6PLCG1
Acetone SCHEMBL27734117 0.91 CA1 (0.54) CA1CA2CA4CA6PLCG1
SCHEMBL28503089 0.81 CA1 (0.58) CA1CA2CA4CA6PLCG1
SCHEMBL8106699 0.81 LOX (0.47) CA1CA2CA4CA6L3MBTL1
SCHEMBL2779909 0.79 CA1 (0.45) CA1CA2CA4CA6PLCG1
SCHEMBL2475835 0.79 CA1 (0.68) CA1CA2CA4CA6PLCG1
SCHEMBL38660050 0.79 CA1 (0.68) CA1CA2CA4CA6PLCG1
SCHEMBL456613 0.78 CA2 (0.48) CA1CA2CA4CA6PLCG1
SCHEMBL29878430 0.78 CA2 (0.48) CA1CA2CA4CA6PLCG1
SCHEMBL2781407 0.78 CA1 (0.43) CA1CA2CA4CA6PLCG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116854631-B 4-Aryl-2-pyridone compound and preparation method thereof 安徽中医药大学 2025-04-15 CN claimed
CN-116854631-A 4-aryl-2-pyridone compound and preparation method thereof 安徽中医药大学 2023-10-10 CN claimed
CN-109678811-A A kind of asymmetric preparation method of florfenicol intermediate cyclic product 湖北中牧安达药业有限公司 2019-04-26 CN claimed
CN-117820191-B Diphenylamine compound and preparation method, application and pharmaceutical composition thereof FUDAN UNIVERSITY (CN) 2026-05-26 CN disclosed
EP-4743453-A1 MODULATORS OF MITOCHONDRIAL DNA REPLICATION Pretzel Therapeutics, Inc. (US) 2026-05-20 EP disclosed
CN-122070618-A Graphite-based electrochemical cell 铌博尔特有限公司 2026-05-19 CN disclosed
WO-2026099505-A1 SYSTEM FOR CONTROLLING BATTERY TEMPERATURE NYOBOLT LIMITED (GB) 2026-05-15 WO disclosed
EP-4634118-B1 NIOBIUM METAL OXIDE NYOBOLT LTD (GB) 2026-04-22 EP disclosed
US-20250337004-A1 COMPOSITE POLYMER CERAMIC ELECTROLYTE HSBC VENTURES USA INC. 2025-10-30 US disclosed
EP-4634118-A1 NIOBIUM METAL OXIDE Nyobolt Limited (GB) 2025-10-22 EP disclosed
EP-4623496-A1 CHARGING AND DISCHARGING SYSTEM Nyobolt Limited (GB) 2025-10-01 EP disclosed
EP-1415983-A1 5-AMIDINO-N-(2-AMINOPHENETHYL)-HYDROXYBENZENESULFONAMIDE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND INTERMEDIATE THEREFOR Kissei Pharmaceutical Co., Ltd. (JP) 2004-05-06 EP disclosed
US-6071927-A Spiro-piperidine derivatives and their use as therapeutic agents MERCK SHARP & DOHME LTD. (GB) 2000-06-06 US disclosed
CN-1223656-A Spiro-piperidine derivatives and their use as therapeutic agents MERCK SHARP & DOHME (GB) 1999-07-21 CN disclosed
EP-0906315-A1 SPIRO-PIPERIDINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS MERCK SHARP & DOHME LTD. (GB) 1999-04-07 EP disclosed
CN-1042539-C 11,21-bisphenyl-19-norpregnane derivatives AKZO NOBEL NV (NL) 1999-03-17 CN disclosed
WO-1997049710-A1 SPIRO-PIPERIDINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS MERCK SHARP & DOHME LIMITED (GB) 1997-12-31 WO disclosed
EP-0451007-B1 Sulphonylphenyl-beta-D-thioxylosides, process for their preparation and their use in therapy FOURNIER IND & SANTE (FR) 1995-11-08 EP disclosed
US-5100913-A Venous antithrombotics FOURNIER INDUSTRIE ET SANTE (FR) 1992-03-31 US disclosed
EP-0451007-A1 Sulphonylphenyl-beta-D-thioxylosides, process for their preparation and their use in therapy FOURNIER INDUSTRIE ET SANTE (FR) 1991-10-09 EP disclosed