Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iniparib SCHEMBL242006 | 0.84 | PARP1 (1.00) | PARP1GAAALDH1A1PKML3MBTL1 | |
| Iniparib SCHEMBL29354973 | 0.84 | PARP1 (1.00) | PARP1GAAALDH1A1PKML3MBTL1 | |
| SCHEMBL10249696 | 0.76 | PARP1 (0.58) | PARP1ALDH1A1L3MBTL1TSHRLCK | |
| SCHEMBL858826 | 0.72 | PARP1 (0.55) | PARP1GAAALDH1A1L3MBTL1TSHR | |
| SCHEMBL435829 | 0.72 | PARP1 (0.55) | PARP1ALDH1A1L3MBTL1TSHRLCK | |
| SCHEMBL15539961 | 0.71 | PARP1 (0.53) | PARP1ALDH1A1L3MBTL1TSHRLCK | |
| SCHEMBL444401 | 0.71 | PARP1 (0.53) | PARP1ALDH1A1TSHRLCKSMN1; SMN2 | |
| SCHEMBL1254186 | 0.69 | PARP1 (0.71) | PARP1GAAALDH1A1PKML3MBTL1 | |
| SCHEMBL10962857 | 0.68 | LCK (0.53) | PARP1GAAALDH1A1L3MBTL1TSHR | |
| SCHEMBL10594355 | 0.68 | LCK (0.53) | PARP1GAAALDH1A1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9474688-B2 | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients | CORNING INCORPORATED (US) | 2016-10-25 | — | — | US | disclosed |
| WO-2014008592-A1 | COMBINATIONS COMPRISING DIAMIDINE COMPOUNDS AND PARP INHIBITORS FOR USE IΝ TREATING CANCER | ONCOZYME PHARMA INC. (CA) | 2014-01-16 | — | — | WO | disclosed |